Microparticulate systems

Microparticulate Systems - Although dual combination treatment systems comprising microparticles and flocculants have been used in the paper industry since the 1980s, it is only recently that there has been a general trend for paper mills to switch from conventional single component systems to dual systems. 

Andrianov AK, Payne LG (1996) In Cohen S, Bernstein H (eds) Microparticulate systems for the delivery of propetins and vaccines. Dekker, New York, chap 4, p 127... 

MJ Alonso. Nanoparticulate drug carrier technology. In S Cohen, H Bernstein, eds. Microparticulate Systems for the Delivery of Proteins and Vaccines. New York Marcel Dekker, 1996, pp 203-242. 

Microparticulate Systems for the Delivery of Proteins and Vaccines, edited by Smadar Cohen and Howard Bernstein... 

Amselem, S., Delivery Systems for Vaccines, in Microparticulate Systems for Drug Delivery, S. Cohen and H. Bernstein, eds., Marcel Dekker, New York, 1996, 149. 

As noted earlier, gelatin can be converted to macro- or microparticulate systems, depending on the conditions of preparation. 

Microparticulate Systems for the Delivery of Proteins and Vaccines, edited by Smadar Cohen and Howard Bernstein Good Manufacturing Practices for Pharmaceuticals A Plan for Total Quality Control, Fourth Edition, Revised and Expanded, Sidney H. Willig and James R. Stoker... 

Microparticulate systems present the advantage, in comparison with single-unit solid systems, to guarantee a wider contact area between the drug and the mucosa. Different microparticulate systems intended for vaginal administration were developed they include liposomes, microcapsules, and microspheres. Such systems can possess intrinsic bioadhesive properties or can be loaded in a vehicle with bioadhesive properties. 

Different drug delivery systems have been proposed for vaginal delivery of peptides and proteins. The first one was a mucoadhesive gel based on polyacrylic acid intended for vaginal administration of insulin [96]. More recently, microparticulate systems such as starch and hyaluronan ester (HYAFF) microspheres have been proposed for vaginal delivery of insulin... 

Microparticulate systems are being investigated for both vaginal drag and vaccine delivery ... 

Describe the possible reasons for enhanced vaginal vaccination using microparticulate systems. 

Schwendeman, S. P, Cardamone, M., Klibanov, A., and Langer, R. (1996), Stability of proteins and their delivery from biodegradable polymer microspheres, in Cohen, S., and Bernstein, H., Eds., Microparticulates Systems for the Delivery of Proteins and Vaccines, Marcel Dekker, New York, pp. 1 49. 

Chitosan microparticulate systems have also been investigated for vaccine nasal delivery and have proven to induce strong systemic and mucosal immune responses [18,21,76],... 

Kas HS (2004) Drug delivery to brain by microparticulate systems. Adv Exp Med Biol 553 221-230. 

Igartua, M. Hernandez, R.M. Esquisabel, A. Gascon, A.R. Calvo, M.B. Pedraz, J.L. Influence of formulation variables on the in-vitro release of albumin from biodegradable microparticulate systems. J. Microencapsul. 1997,14 (3), 349-356. 

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