Microchip Electrophoresis with Amperometric Detection for Organic Food Analytes

1 Microchip Electrophoresis with Amperometric Detection for Organic Food Analytes 

Detection of (natural) antioxidants, especially of polyphenolic compounds and vitamins, has been one of the most relevant and earliest studied examples on ME-AD in the field of 

Glassy carbon electrode (GCE) aligned to ME has also been explored for the fast and simultaneous detection of prominent natural antioxidants including examples of flavonoids and ascorbic acid [25]. Determination involved the electrophoretic separation of arbutin, (-l-)-catechin, and ascorbic acid in less than 4 min as well as the separation of different couples of natural antioxidants of food significance such as (-l-)-catechin and ascorbic acid, (-l-)-catechin and rutin, or arbutin and phlorizdin. 

The analysis of antioxidants in olive oil has also been explored using ME-AD. Three phenolic compounds (tyrosol, hydroxytyrosol, and oleuropein glucoside) were determined on real extra virgin olive oil samples adopting end-channel amperometric detection [31]. 

Amines have been also studied using ME-AD technology. A homemade miniaturized CE-AD system (Cu working electrode), has also been proposed for the fast determination of bioactive amines [32]. Because their formation and metabolism widely occur in living organisms, they are also present in a variety of different foods, primarily as a consequence of microbial amino-acid decarboxylation. The proposed method allowed three bioactive 

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