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Microarrays genotyping applications

The ultimate goal of microarray-based expression analysis is to acquire a comprehension of the entire cellular process, in order to exploit and to standardize the multidi-menisional relations between genotype and phenotype. However, an increasingly important parameter, which has not yet been substantially taken into account, is the role of cellular translation. This means that mRNA expression data need to be correlated with the assortment of proteins actually present in the cell. One approach is based on the use of microarrays containing double-stranded DNA probes for the analysis of DNA-protein interaction and, thus, the detection and identification of DNA-binding proteins by means of fluorescence [130] or mass spectrometry analysis [131]. Moreover, substantial efforts are currently under way to develop protein, antibody, or even cell arrays, applicable to the cor-... [Pg.418]

Application of Novel Genotyping Microarray Technologies in Cancer Research... [Pg.47]

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See also in sourсe #XX -- [ Pg.581 ]



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Genotype

Genotype / genotyping

Genotypic

Genotyping

Genotyping applications

Microarray

Microarray applications

Microarrays

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