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Swiss—Webster mice

Mouse (Swiss- Webster) once (GW) 1041 M (LDso) 1363 F (LDso) Hart 1976... [Pg.30]

Mouse (Swiss- Webster) 30 min Resp 60 M (DC ) Matijak-Schaper and Alarie 1982 HCN... [Pg.29]

Mouse (Swiss- Webster) 9 hr Hepatic 4500 F (Increased SGPT activity)... [Pg.27]

Mouse (Swiss- Webster) 30-180 min Resp 0.17 (RDso for 180 min exposure) Sanghaetal. 1981 HDI... [Pg.33]

Mouse (Swiss- Webster) Gd 0 - PND 180 spleen weights depressed spleen ceil concentrations of interleukin-2, interferon-g and tumor necrosis factor-a deficiency of 004-1- cells in T-cell populations) Golub et al. 1993b C,HlsAIO,... [Pg.57]

Mouse (Swiss- Webster) 6 wk (F) 62b F 130 F (decreased total, vertical, and horizontal activity decreased diurnal period shortened activity periods) Golub et al. 1989 C H,sAIO ... [Pg.57]

Mouse (Swiss-Webster) Gd 1-PND 170 (F) 7.5 155 (decreased fore- and hindlimb gripstrength and decreased air puff startle response) Golub et al. 1995 csh,saio9 ... [Pg.60]

Mouse (Swiss-Webster) 10 wk 7 d/wk (F) 0.65 1.3 (increased mortality in offspring) Thomas and Hinsdiil 1979... [Pg.132]

Mouse (Swiss- Webster) Gd 6-15 6 hr/d 10 20 (decreased circulating erythroid precursors, elevation of granulocytic Keller and Snyder 1988... [Pg.34]

Mouse (Swiss- Webster) 10 min Resp 153M (20% decrease in respiratory rate) Kane et al. 1980... [Pg.39]

Mouse (Swiss-Webster) 60 min 220 M (LCso) Gibson and Roberts 1972... [Pg.23]

SVA. Sister chromatid exchange, Swiss-Webster mouse bone marrow + 1 ip X 1 Conner etal. (1983)... [Pg.189]

DVA, DNA strand breaks, eross-links or related damage, Swiss-Webster mouse liver eells in vivo... [Pg.657]

Botulinum toxin is one of several toxins produced by the bacterium Clostridium botulinum. The toxin binds with high affinity to peripheral cholinergic nerve endings, such as those at the neuromuscular junction and in the autonomic nervous system, preventing the release of the neurotransmitter acetylcholine (1). This action at the neuromuscular junction can cause weakness and even paralysis of the muscles supplied by the affected nerves. Sprouting of the terminal nerves eventually results in re-innervation of the muscles and return of function. Doses are measured in mouse units (MU), IMU being the LD50 in Swiss-Webster mice. [Pg.551]

At 50 mg/kg the bioavailability of oxazepam in rats (< 50 per-cent) was lower than in Swiss-Webster mice (> 80 percent). Based on the maximum plasma concentration achieved (Cmax), dose proportionality was not observed in rats or mice after gavage dosing. In the B6C3F1 mouse dosed-feed study, plasma concentrations increased proportionally with concentration of oxazepam in feed. [Pg.286]

Micronucleus formation, male and female Swiss-Webster mouse bone-marrow cells in vivo - 1750 ip X 1 [212]... [Pg.375]

Figure 2. Serum titers of two individual BALB/c mice ( 5, Figure 2a and 1, Figure 2b) immunized with styrene oxide-modified Swiss-Webster mouse hemoglobin. The antisera is titered against the immunogen, SO-modlfied S-W mouse Hb, (filled squares), styrene oxide-modified human hemoglobin (filled triangles), and unmodified human hemoglobin (open squares). Figure 2. Serum titers of two individual BALB/c mice ( 5, Figure 2a and 1, Figure 2b) immunized with styrene oxide-modified Swiss-Webster mouse hemoglobin. The antisera is titered against the immunogen, SO-modlfied S-W mouse Hb, (filled squares), styrene oxide-modified human hemoglobin (filled triangles), and unmodified human hemoglobin (open squares).
See other pages where Swiss—Webster mice is mentioned: [Pg.66]    [Pg.56]    [Pg.28]    [Pg.24]    [Pg.57]    [Pg.58]    [Pg.58]    [Pg.58]    [Pg.59]    [Pg.59]    [Pg.60]    [Pg.128]    [Pg.112]    [Pg.81]    [Pg.248]    [Pg.253]    [Pg.161]    [Pg.45]    [Pg.1501]    [Pg.1501]    [Pg.184]    [Pg.207]    [Pg.317]    [Pg.98]    [Pg.52]    [Pg.190]    [Pg.136]    [Pg.414]    [Pg.293]    [Pg.295]    [Pg.297]   
See also in sourсe #XX -- [ Pg.58 ]



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