MHC major histocompatibility

Autoimmune Disease. Figure 2 Generation of autoreactivity. APC, antigen presenting cell IFN, interferon LPS, lipopolysaccharide MHC, major histocompatibility complex T, T-lymphocyte TCR, Tcell (antigen) receptor TLR, toll like receptors. For details see text. 

MEL Metabolic equivalent level MEM Minimal essential medium MG Myasthenia gravis MGSA Melanoma-growth-stimulatory activity MHC Major histocompatibility complex... 

MHC Major histocompatibility complex ORx3 Oriented to time, place, and person... 

Apo E, apolipoprotein E CAD, coronary artery disease FKN, fractalkine MHC, major histocompatibility complex MCP-1, monocyte chemoattractant protein 1 MMPs, matrix metalloproteinases NK, natural killer oxLDL, oxidized LDL RANTES, regulated on activation, normal T cell expressed and secreted VSMCs, vascular smooth muscle cells. 

Fig. 14.3 Tumor necrosis factor (TNF) locus with some of the polymorphic sites known within the TNF locus. C2, C4, complement C2, C4 Ch, chromosome HLA, human leukocyte antigen HSP, heat shock protein LTA, lymphotoxin A LTB, lymphotoxin B MHC, major histocompatibility complex. (Reproduced from ref 74 by permission of Future Medicine Ltd.)...

ETN, etanercept IL, interleukin INF, infliximab MHC, major histocompatibility complex PBMC, peripheral blood mononuclear cell SNP, single-nucleotide polymorphism. 

Fig. 11.1. Principle of an immunological synapse. Possibilities for communication between B and T cells during an immune response. Antigenic peptides are presented by the MHC complex class II at the surface of the B cell. The antigens are recognized and bound by T cell receptors of the T cell. The T cell receptor is activated and sets a signal chain in motion that leads to activation of the expression of cytokines, such as IL-2. The cytokine is secreted, and binds and activates a cytokine receptor on the B cell. TNFa is shown as another example of a ligand-receptor system. TNFa communicates, as a membrane-bound ligand, with a corresponding receptor on the surface of the B cell. The interactions shown take place in a narrow spatial region between B and T cells, which is why this system is referred to as an immunological synapse. TNF tumor necrosis factor MHC major histocompatibility complex IL-2 interleukin 2.

LFA Leukocyte function-associated antigen MAB Monoclonal antibody MHC Major histocompatibility complex NK cell Natural killer cell... 

IGIV Immunoglobulin intravenous LAK cell Lymphokine-activated killer cell LFA Lymphocyte functional antigen MAb Monoclonal antibody MHC Major histocompatibility complex MCP-1 Macrophage chemotactic protein-1 MIP-1 Macrophage inflammatory protein-1 NK cell Natural killer cell... 

Figure 32.7. Mechanism underlying UVR-induced immune suppression. Uroconic acid, membrane lipids, and DNA are molecular targets. Langerhans cells and keratinocytes are the cellular targets. Mediators produced by skin cells have both local and systemic effects. Abbreviations MHC, major histocompatibility complex ICAM, intracellular adhesion molecule UCA, urocanic acid IL, interleukin PGE, prostaglandin E.

MHC major histocompatibility complex NRTI nucleoside analogue reverse transcriptase... 

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