Methyl thionochloroformate

Catalytic amounts of dichlorobis(triphenylphosphine)palladium(II), Cul, and triphenylphosphine added to phenylacetylene, methyl dithiochloroformate, and triethylamine, and the mixture allowed to react at room temp, for 15 h product. Y 90 /o. The more stable a,p-acetylenethionocarboxylic acid esters were obtained from methyl thionochloroformate. Alternatively, both classes of compd. were obtainable via the corresponding a,p-acetyleneiminoester salts. F.e.s. K. Hartke et al.. Tetrahedron Letters 20, 1073-6 (1989). 

Of a series of indanylthiocarbamates, to1 indate (2) had significant antifungal properties. It is prepared simply from 5-indanyl thionochloroformate (1) by reaction with N-methyl-m-toluidine. It presumably joins the fairly large family of organic compounds having sulfur divalently bound to carbon which are useful topical agents for dermatophytes. 

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