2- Methyl-2-propyl-2-phosphonic acid

C12H27O4P (l-hydroxy-l-methyl-propyl)-phosphonic acid... 

B) The preparation of (cis-1,2-epoxypropyi)phosphonic acid [ (1 -chloroethoxy )chloro-methyl] phosphonic acid (1.0 g) is added with stirring to tetrahydrofuran (50 ml) to which has been added a crystal of iodine and a zinc-copper couple (15.0 g). The mixture is then heated under reflux for 24 hr and the resulting solution filtered to yield (cis-1,2-epoxy propyl )-phosphonic acid. 

Abbreviations N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), L(+)-2 amino-3-phosphonopropionic acid (L-AP3), 6-cyano-7-nitroqninoxaline (CNQ5Q, 2,3-dihydroxy-6-nitro-7-sulfamyl-benzo-f-quinoxaline (NBQX), 3-(2-carboxypiperazin-4-yl)-propyl-l-phosphonic acid (CPP), 7 Chlorokynnreic... 

Goettl, V. M. and Larson, A. A. Antinociception induced by 3-((+-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), an N-methyl-D-aspartate (NMDA) competitive antagonist, plus 6,7-dinitroquinoxaline-2,3-dione (DNQX), a non-NMDA antagonist, differs from that induced by MK-801 plus DNQX, Brain Res. 1994, 642, 334-33. 

Phosphonic Acid, Methyl-, Bis(3-(Trimethoxysilyl)propyl) Ester [CAS 67812-18-4] Schedule 2... 

Of the methods of synthesis of cellulose esters, the one that has been most thoroughly studied is the reaction of trans-esterification, and this method is widely used for the synthesis of low-molecular-weight esters. The alcoholysis of a low-molecular-weight ester (methyl- and n -propyl-borate) with hydroxyl groups of cellulose was first used (37) for die preparation of cellulose borate. This was followed by the trans-esterification, with cellulose, of the esters of phosphorous acids (see above), i.e. mono-, di- and trimethylphosphites (71, 72, 75), esters of phosphonic acids (76), and also phenyl-/ -chloroethyl- and / -fluoroethylphosphites (77, 78). Of considerable interest is the reaction of alcoholysis, with cellulose, of the esters of aryl- and naphthalenesulphonic add, which results in the formation of cellulose ethers, rather than esters (79-81). 

Fig. 1 HPLC-ESP MS reconstructed (total) ion chromatogram from a standard mixture of alkyl phosphonic acids at a concentration of 1 p-g/ml each 1) methylphosphonic acid (MPA) 2) ethylphosphonic acid (EPA) 3) methyl ethylphosphonic acid (MEPA) 4) ethyl methylphosphonic acid (EMPA) 5) ra-propylphosphonic acid (nPrPA) 6) ethyl ethylphosphonic acid (EEAP) 7) isopropyl methylphosphonic acid (iPrMPA) 8) n-propyl methylphosphonic acid (nPrMPA) 9) isopropyl ethylphosphonic acid (iPrEPA) 10) n-propyl ethylphosphonic acid (nPrEPA) 11) isohutyl methylphosphonic acid (iBuMPA) 12) cyclohexyl methylphosphonic acid (CHMPA) 13) pinacolyl methylphosphonic acid (PinMPA).

There is not any critical hypoxic threshold for modification of the 3-(2-carboxypiperazin-4-yl) propyl-1-phosphonic acid high-affinity binding site of the N-methyl-D-aspartate receptor, but modification is coupled to a gradual decrease in brain cell energy metaboUsm and increase in hpid peroxidation (Fritz et al. 2001). 

Common comonomers are those that place carboxylic, sulfonate, phosphite, polyethylene glycol, or hydrophobic groups along the backbone. They include maleic anhydride (subsequently hydrolyzed), sodium 2-acrylamido tert-butylsulfonic acid (Na-ATBS), sodium styrene sulfonate, l-allyloxy-2-hydroxypropyl sulfonate, l-allyloxy-2-hydroxypropyl phosphite, vinyl phosphonic acid, vinyl acrylate, polyethoxy acrylate, ethyl acrylate, methyl vinyl ether, and hydroxyl propyl acrylate [2,47-50]. 

A polymeric dibenzo-16-crown-5 polymers synthesized by reaction with formaldehyde were functionalized with a pendant acid group such as carboxylic acid, phosphonic acid monoethyl ester, phosphonic acid or sulfonic acid and a geminal hydrogen, methyl or propyl group (Fig. 2) [6],... 

Methyl-5-propyl-2,6-dimercapto-4 -... - (2-Methylpropyl)phosphonic acid M-00258 - M-00262... 

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