5-Methyl-2-phenyl-4,5,6,7-tetrahydro

C2oH fiClNO 149968-10-5) see Montelukast sodium [tx5-( )]-3-[2-(7-chloro-2-quinolinyl)ethenyl]-a-[2-[2-(l-methyl-l-[(tetrahydro-2//-pyran-2-yl)oxy]ethyl]phenyll-ethyl]benzenemethanol methanesulfonate (ester) (CjjHjgClNOjS 162489-71-6) see Montelukast sodium (5)-a-[3-[(E)-2-(7-chloro-2-quinolinyI)ethenyl]phenyl]-2-(l-hydroxy-l-methylethyl)benzenepropanol (C2i,H2xClN02) see Montelukast sodium (5)-a-[3-[( )-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-2-(l-hydroxy-l-methylethyl)benzenepropanol methanesulfonate... [Pg.2336]

Aus den entsprechenden 5-Benzyl-3,7-diaryl-3,4,6,7-tetrahydro-5H-l,2,5-triazepinen erhalt man beim Kochen mit Brom in Methanol l-Benzyl-4-phenyl-imidazoI (49%) bzw, 1-Benzyl-4-(4-methyl-phenyl)-imidazol (36%). Bei 20° entstehen dagegen die entsprechenden 3,6-Diaryl-pyridazine443. [Pg.94]

Die intramolekulare Amin-Addition bei 1-Aryl-l-[2-(methylamino-methyl)-phenyl]-l-al-kenen unter Bildung von 1,2,3,4-Tetrahydro-isochinolinen wird durch Kaliumhy-droxid katalysiert2. [Pg.757]

Benzoyl-l-(4-brom-phenyl)-4,5-dimethyl-l. 2,3,6-tetrahydro-pyridin (52% bez. auf die Gesamtreaktion)2 2- Benzoyl-4,5-dimethyl-1-( 4-methyl-phenyl)-l, 2,3,6-telrahydro-pyridin (36% bez. auf die Gesamtreaktion)2 2-Benzoyl-4,5-dimethyl-l-phenyl-l,2,3,6-tetrahydro-pyridin (52% bez. auf das intermediate O-Silyl-hydroxylamin-Derivat)2... [Pg.1051]

Fig. 9. Chemical structure of the synthetic neurotoxin l-methyl-4-phenyl-tetrahydro-pyridine (MPTP) and its metabolism, with monoamine oxidase B as substrate, via MPDP+ to the methyl-phenyl-pyridinium ion (MPP+), which is the active toxin. (For further details see Feldman (1997).)...

The product of Step 6, (II), was subsequently converted into (4R,5R)-l-((4-(4-(3, 3-dibutyl-7-(dimethylamino)-2,3,4,5-tetrahydro-4-hydroxy-l,l-dioxido-l-benzithiepin-5-yl)phenoxy)methyl)phenyl)-methyl-4-aza-l-azabicyclo[2.2.2]octane chloride, (III), as illustrated in Eq. 2 and is described 4. [Pg.631]

Imidazol 2-Mercapto-1-phenyl-tetrahydro- IV/Id, 252 IsothioharnstofT N-Benzyl-S-methyl-E4, 604 (aus dem Salz)... [Pg.632]

Chlor-5-methyl-2-oxo-5-phenyl-tetrahydro- El9a, 662 (Carbon-saure + En/Lacton-Bildung)... [Pg.861]

Fnran 3,3-Dichloro-4-methyl-2-phenyl-tetrahydro- E21c, 2257 [C13C — CH(Ar) — OAllyl + RjSnH]... [Pg.872]

E19a, 653 [Carbonsaure + En/ Cyclisierung (intra)] trani-2-Methyl-5-oxo-3-phenyl-tetrahydro- E2Ib, 1194 (3-Ar-2,5-dioxo-THF + H3C-Li/TiCI4)... [Pg.879]

Chlor-2,2-di methyl-1 -phenoxy-EI9b, 1661 (Carben + En) trans,/cis-2-(2-Chlor-ethoxy)-1 -phenyl- IV/3, 246 Furan 3-Chlor-4-methyl-2-phenyl-tetrahydro- E2Ic, 2257 [C12CH — CH(Ar) —O-Allyl + R3SnH] Pent an... [Pg.882]

Pyrazin 2-Anilinocarbonyl-3,4,5,6-tetrahydro- IV/lc, 324 Pyrrolidin l-[2(bzw. 3- bzw. 4)-Methyl-phenyl]-2-nitrosimino-E14b, 748 (N-Nitrosier.)... [Pg.889]

Ethan l-Acetamino-l-(4-methyl-phenyl)-2-nitro- E16d, 162 (En + NOf + R-CN) Hydroxylamin l-(4-Nitro-phenoxy)-E16a, 306 (Amin-oxid-Umlager.) Isoquinolin l-Hydroxyamino-5,6-methylendioxy-2-methyl-l, 2,3,4-tetrahydro- E16a, 13 (OH - NH-OH)... [Pg.895]

Cyclohuten 2-Dimethylamino-3,4-dioxo-1 -(4-methyl-phenyl)-E15/2, 1444 (H Ar) Cyclopenta g indol 1-Methoxycarbo-nyl-l,6,7,8-tetrahydro- E6b/1,... [Pg.1129]

Furan 3-Ethyl-4-(4-methyl-phenyl-sulfinyl)-2-oxo-tetrahydro- E21b, 1813 [Ar— SO —(CHj)j — COOH + H5C2-CHO]... [Pg.1157]

Oxazin 3-Hydroxy-6-methoxy-carbonyl-6-methyl-4-phenyl-tetrahydro- E16a, 189 (aus... [Pg.1163]

Dimethyl-4-(4-methyl-phenyl-sulfonyl)-tetrahydro- E19a, 1123 [R — Br + En (rad.) (intra)]... [Pg.1171]

Another synthesis of side-chain-hydroxylated cholesta-5,7-dien-3/S-ol derivatives uses the aldehyde (386), prepared by ozonolysis of the adduct of ergosteryl acetate with 4-phenyl-l,2,4-triazoline-3,5-dione. An aldol condensation between the aldehyde (386) and the pre-formed enolate of 3-methyl-3-tetrahydro-pyranyloxybutan-2-one (387) led to the enone (388), after acidic work-up. Reduc-... [Pg.295]

Athoxy-2-(2-alhoxy-alhyl)- 1280 5-Athoxy-2-isopropyl- 1280 5-Athoxy-2-methyl- 1280 5-Athoxy-2-phcnyl- 1280 2,5-Diphenyl- 1137 2-Methyl-5-phenyl- 1277 5-Oxo-4-athyl-2-phenyl-tetrahydro- 1273 2-Oxo-3-phenyl-2,3-dihydro- 573 2-Phenyl-5-(4-nitro-phcnyl)- 1137... [Pg.773]

Natrium in fl. Ammoniak kann zur Spaltung cyclischer quartarer Ammoniumsalze her-angezogen werden z.B. bildet 2,2-Dimethyl-1,2,3,4-tetrahydro-isochinoliniumjodid Dimethyl-[2-(2-methyl-phenyl)-athyl]-amin [mit Amalgam erhalt man Dimethyl-(2-vi-nyl-benzyl)-amin] (s. Bd. XI/1, S. 974). Zur Reduktion mit Natrium/fl. Ammoniak s.a. Lit.3 4. [Pg.675]

Amino-phenyl)- 306 2-(2-Amino-phenyl)-4,5,6,7-tetrahydro- 306 2-(4-Chlor-phenyl)- 607 2-( 4-Methyl-phenyl)- 607 2-(2-Nitro-pheny )- 608 2-Phenyl- 607... [Pg.867]

Transformations of a six-membered ring into a 1,2,3-triazine connectivity are rare. Two isomeric A -amino-4-methyl- (phenyl-) quinazolin-2-ones have been transformed with LTA into 4-methyl- (phenyl-) 1,2,3-benzotriazine in 23-24% yield <1975J(P1)31> see also CHEC(1984). A recent example is the rearrangement of the cyclic nitrosourea 289 under the influence of strong alkali into the unstable tetrahydro-l,2,3-triazine 11 (Equation 129) <1997SC1569> see also <2006BML427>. [Pg.81]

When o-(2-aminoethyloxy)benzophenone (27) was refluxed in pyridine, the cychc imine (28) was generated, which was then methylated and reduced with LiAlH4 to give the 5-phenyl-tetrahydro-... [Pg.221]

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