5- Methyl phenazinium

ISHizu, K., H. H. Dearman, M. T. Huang, and J. R. White Electron Paramagnetic Resonance Observations on Biogenic Semiquinone and 5-Methyl Phenazinium Radicals. Biochem. Biophys. Acta 165, 283 (1968). 

Alcohol Electrodes were prepared by layering 20 iL of a saturated solution of N-methyl phenazinium-tetracyanoquinodimethane onto a base graphite electrode. After drying, these electrodes were dipped in N-cyclohexyl-n (2-morpholinoethyl) -carbodimide methylpotoluene sulphonate for 90 minutes. They were then washed in carbonate buffer pH 9.8 and immersed in a solution of alcohol oxidase and peroxidase, and stabilized at various pH values. Electrodes were vacuum dried and stored under vacuum. 

Tetracyanoquinodimethane (TCNQ) and many of its derivatives are easily reduced to anions of the type TCNQ-, which form salts with various cations. With many cations, e.g., tetrathiafulvalene cations (TTF+), and N-methyl phenazinium cations (NMP+), the TCNQ- anions form electronically conducting salts (- molecular metals, -> charge-transfer complexes) that can be used as electrodes, especially because of their electrocatalytic properties (- biosensors, -> electrocatalysis, -> molecular metals) [i,ii]. TCNQ undergoes insertion electrochemical reactions (-> insertion electrochemistry) leading to TCNQ salts [iii, iv]. Polymers... 

Dimethylaminoindamines undergo rapid intramolecular cyclization to give the 2,8-diamino-10,10-dimethyl-5,10-dihydrophenazinium ion which is slowly converted into the lO-methyl-phenazinium salt, a methyl group being eliminated as methanol." ... 

Various redox compounds that fulfil catalyst characteristics have been investigated in systems with recycling of NAD by electrocatalytic methods. Quinones, formed either by oxidation of carbon surfaces [143, 145] or adsorbed to the electrode surface [146, 147], phenazines [148, 149], phenoxazine derivatives such as Meldola Blue [182], 9-naphthoyl-Nile Blue [151, 152] and l,2-benzophenoxazine-7-one [153], and also the organic conducting salt N-methyl phenazinium tetracyanoquinodimethanide (TTF TCNQ") [154, 155], ferricinium ions [156, 157] and hexacyanoferrat(IIl) ions [158, 159] can act as catalysts for the electrochemical oxidation of NADH. It is assumed that in corresponding electron-transfer reactions a charge-transfer complex between the immobilized mediator and NADH is formed. The intermediate reduced redox mediator will be reoxidized electrochemically. Most systems mentioned, however, suffer from poor electrode stabilities. 

Electropolymerized films of mediator species, such as mercaptoquinone, N-methyl phenazinium ion, and thionine (a redox dye), were also shown to mediate NADH oxidation, although in these latter cases, the structure of the electropolymerized film is not well-established. 

Verbindung yon N-Methyl-phenazinium> hydroxyd mit 9-Methyl-9.10-dihydro-phenazin 23 I 59. 

In In waBriger Salzsaurc wird 1-Carboxy-phenazin und 5-Methyl-1 -carboxy-phenazinium Salz zu 1-Hydroxy-phenazin (5%d.Th.) bzw. l-Hydroxy-5-methyl-phena-ziniurn Salz (5% d.Th.) abgebaut1 ... 

Both l-carboxy-5-methyl[6,7,8,9- H4]phenazinium betaine (as 171) and 1-carboxy[6,7,8,9- H4]phenazine (as 170) were incorporated efficiently into pyocyanin (173) without loss of deuterium. Hydroxylation of (171) thus occurs, as a specific decarboxylative reaction. This specificity, together with the high level of incorporation of these two compounds, strongly suggested that they are normal intermediates in pyocyanin biosynthesis and since 1-hydroxy-... 

CA Index Name Phenazinium, 3,7-diamino-2,8-di-methyl-5-phenyl-, chloride (1 1)... 

Amino-3-sulfophenyl)amino]-7-[ethyl[ 3-sulfopheny[) methyl amino]-5- 4-sulfophenyl)phenazinium hydroxide inner salt. C.I. 50230. C.l. Acid blue 18... 

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