Methyl-dinitrophenols

An ipso attack on the fluorine carbon position of 4-fIuorophenol at -40 °C affords 4-fluoro-4-nitrocyclohexa-2 5-dienone in addtion to 2-nitrophenol The cyclodienone slowly isomenzes to the 2-nitrophenol Although ipso nitration on 4-fluorophenyl acetate furnishes the same cyclodienone the major by-product is 4 fluoro-2,6-dinitrophenol [25] Under similar conditions, 4-fluoroanisole pnmar ily yields the 2-nitro isomer and 6% of the cyclodienone The isolated 2 nitro isomer IS postulated to form by attack of the nitromum ion ipso to the fluorine with concomitant capture of the incipient carbocation by acetic acid Loss of the elements of methyl acetate follows The nitrodienone, being the keto tautomer of the nitrophenol, aromatizes to the isolated product [26] (equation 20) Intramolecular capture of the intermediate carbocation occurs in nitration of 2-(4-fluorophenoxy)-2-methyIpropanoic acid at low temperature to give the spiro products 3 3-di-methyl-8 fluoro 8 nitro-1,4 dioxaspiro[4 5]deca 6,9 dien 2 one and the 10-nitro isomer [2d] (equation 21)... 

Crystal violet Thymol blue 2,4-Dinitrophenol Bromophenol blue Bromocresol green Methyl red Alizarin Bromothymol blue Phenol red Phenolphthalein Alizarin yellow R... 

AI3-00040, see Cyclohexanol AI3-00041, see Cyclohexanone AI3-00045, see Diacetone alcohol AI3-00046, see Isophorone AI3-00050, see 1,4-Dichlorobenzene AI3-00052, see Trichloroethylene AI3-00053, see 1,2-Dichlorobenzene AI3-00054, see Acrylonitrile AI3-00072, see Hydroquinone AI3-00075, see p-Chloro-rrr-cresol AI3-00078, see 2,4-Dichlorophenol AI3-00085, see 1-Naphthylamine AI3-00100, see Nitroethane AI3-00105, see Anthracene AI3-00109, see 2-Nitropropane AI3-00111, see Nitromethane AI3-00118, see ferf-Butylbenzene AI3-00119, see Butylbenzene AI3-00121, see sec-Butylbenzene AI3-00124, see 4-Aminobiphenyl AI3-00128, see Acenaphthene AI3-00134, see Pentachlorophenol AI3-00137, see 2-Methylphenol AI3-00140, see Benzidine AI3-00142, see 2,4,6-Trichlorophenol AI3-00150, see 4-Methylphenol AI3-00154, see 4,6-Dinitro-o-cresol AI3-00262, see Dimethyl phthalate AI3-00278, see Naphthalene AI3-00283, see Di-rj-butyl phthalate AI3-00327, see Acetonitrile AI3-00329, see Diethyl phthalate AI3-00399, see Tributyl phosphate AI3-00404, see Ethyl acetate AI3-00405, see 1-Butanol AI3-00406, see Butyl acetate AI3-00407, see Ethyl formate AI3-00408, see Methyl formate AI3-00409, see Methanol AI3-00520, see Tri-ocresyl phosphate AI3-00576, see Isoamyl acetate AI3-00633, see Hexachloroethane AI3-00635, see 4-Nitrobiphenyl AI3-00698, see IV-Nitrosodiphenylamine AI3-00710, see p-Phenylenediamine AI3-00749, see Phenyl ether AI3-00790, see Phenanthrene AI3-00808, see Benzene AI3-00867, see Chrysene AI3-00987, see Thiram AI3-01021, see 4-Chlorophenyl phenyl ether AI3-01055, see 1.4-Dioxane AI3-01171, see Furfuryl alcohol AI3-01229, see 4-Methyl-2-pentanone AI3-01230, see 2-Heptanone AI3-01231, see Morpholine AI3-01236, see 2-Ethoxyethanol AI3-01238, see Acetone AI3-01239, see Nitrobenzene AI3-01240, see I idine AI3-01256, see Decahydronaphthalene AI3-01288, see ferf-Butyl alcohol AI3-01445, see Bis(2-chloroethoxy)methane AI3-01501, see 2,4-Toluene diisocyanate AI3-01506, see p,p -DDT AI3-01535, see 2,4-Dinitrophenol AI3-01537, see 2-Chloronaphthalene... 

Methyl-l,3-dinitrobenzene, see 2,6-Dinitrotoluene 2-Methyl-4,6-dinitrophenol, see 4,6-Dinitro-o-cresol 6-Methyl-2,4-dinitrophenol, see 4,6-Dinitro-o-cresol... 

Acetamido-4-amino-6-chloro-s-triazine, see Atrazine Acetanilide, see Aniline, Chlorobenzene, Vinclozolin Acetic acid, see Acenaphthene, Acetaldehyde, Acetic anhydride. Acetone, Acetonitrile, Acrolein, Acrylonitrile, Aldicarb. Amyl acetate, sec-Amyl acetate, Bis(2-ethylhexyl) phthalate. Butyl acetate, sec-Butyl acetate, ferf-Butyl acetate, 2-Chlorophenol, Diazinon. 2,4-Dimethylphenol, 2,4-Dinitrophenol, 2,4-Dinitrotoluene, 1,4-Dioxane, 1,2-Diphenylhydrazine, Esfenvalerate. Ethyl acetate, Flucvthrinate. Formic acid, sec-Hexyl acetate. Isopropyl acetate, Isoamyl acetate. Isobutyl acetate, Methanol. Methyl acetate. 2-Methvl-2-butene. Methyl ferf-butvl ether. Methyl cellosolve acetate. 2-Methvlphenol. Methomvl. 4-Nitrophenol, Pentachlorophenol, Phenol. Propyl acetate. 1,1,1-Trichloroethane, Vinyl acetate. Vinyl chloride Acetoacetic acid, see Mevinphos Acetone, see Acrolein. Acrylonitrile. Atrazine. Butane. 

Nitric acid, see 1-Butene, o-Chloronitrobenzene. p-Chloronitrobenzene, Chloropicrin, 2,3-Dichloronitrobenzene. 3.4-Dichloronitrobenzene. 2,4-Dinitrophenol, Formaldehyde, Isopropylbenzene, Methanol, Methyl mercaptan, 2-Methylphenol, 2-Methylpropene, Methyl sulfide. Nitrobenzene, 2-Nitrophenol, 4-Nitrophenol,... 

The nitration of 2-amino-4,6-dinitrotoluene (63) with a mixtnre of nitric acid in sulfuric and acetic acids yields 2-diazo-3-methyl-4,6-dinitrophenol (65) in 75 % yield without isolation of the intermediate nitramine (64)." ... 

The nitration of both 4-methyl- and 4-chloro-2,6-dinitrotoluenes (66 and 67) with mixed acid in acetic acid at subambient temperature allows the isolation of the nitramines, (68) and (69), respectively. Thermolysis of (68) and (69) in refluxing methylene chloride yields the corresponding diazophenols, (70) and (71), respectively. Scilly and co-workers isolated 2-diazo-4,6-dinitrophenol (DINOL) (53) from the thermolysis of fV,2,3,5-tetranitroaniline (73) in ethyl acetate at 60 °C. 

Fig. 12 Proposed structure of (salen)CoX complex, where X = 2,4-dinitrophenolate and the salen ligand contains the sterically unencumbering methyl substituents...

Cresol red Crystal Violet Malachite Green Methanil Yellow Thymol Blue Orange IV -2,4-Dinitrophenol -Erythrosin, Na2 salt -Dimethyl Yellow Cl 11020 Bromophenol Blue Congo Red Cl 22120 Methyl Orange Bromocresol Green Alizarin Red S Cl 42750 Methyl Red Cl 13020 -Bromocresol Purple Chlorophenol Red p-Nitrophenol Alizarin Bromothymol Blue Brillant Yellow Phenol Red Neutral Red Cl 50040 -m-NItrophenol -Cresol Red Metacresol Purple Phenolphthalein -Thymolphthalein -P-Naphthyl Violet Alizarin Yellow R 2,4,6-T rinitrotoluene... 

Dinitroanilino)- -propanol or 2-Methyl-N-(2 t4 -dinitrophenol)-ethanol-amine. Listed in CA 50, 2694d as N-(2t4-Dinitrophenyl)-alaninol, (OaN)2C6H3.-NH.CH.CHaOH,... 

Figure 8.9 The pH dependence of the /z-octanol-water distribution ratio of pentachlorophenol (PCP, pKj = 4.75), 4-chloro-a-(4-chlo-rophenyl) benzene acetic acid (DDA, pKb = 3.66), 2-methyl-4,6-dinitrophenol (DNOC, pKia = 4.46), and 2,4,5-trichlorophenoxy acetic acid (2,4,5-T, pKia = 2.83). (from Jafvert et al., 1990).

An MIP film was applied in a chemosensor for determination of a 2-methyl-4, 6-dinitrophenol (4,6-dinitro-o-cresol, DNOC) insecticide using SWV transduction... 

Ammonium 2,4,5-trinitroimidazolide, 1141 Ammonium 3-methyl-2,4,6-trinitrophenoxide, 2799 Ammonium picrate, 2315 2-Azido-3,5-dinitrofuran, 1380 2,2 -Azo-3,5-dinitropyridine, 3232 2-Benzylideneamino-4,6-dinitrophenol, 3594 Bis(2,4-dinitrophenyl) disulfide, 3443 Bis(2-nitrophenyl) disulfide, 3459... 

In the case of pesticides which are not ChE inhibitors, exposure is measured by the analysis of blood and/or urine for the active ingredient or its metabolites. Baseline levels of pesticides and/or metabolites are not usually determined, with the exception of methyl bromide. In this case, a blood sample is taken to check for bromide ion before fumigators use the pesticide. Blood and urine tests are run only in the case of spills or other accidents to assist in identifying the cause of poisoning or to monitor workers in a workplace. Paraquat, chlorinated hydrocarbons, mercury, p-nitrophenol, and dinitrophenol are examples of pesticides or metabolites of pesticides that have been found in the urine of exposed workers. 

FIGURE 13.14 A typical LC-MS chromatogram obtained in the scan mode of a preconcentrated aqueous standard solution (a) and of a preconcentrated spiked river water sample (b), as well as of an unspiked preconcentrated river water sample (c). Peak labels denote Ph, Phenol 2,4-DMP, 2,4-dimethylphenol 2-CP, 2-chlo-rophenol 4-CR,4-chlorophenol 4-NP,4-nitrophenol 2-NP,2-nitrophenol 4-C-3-MP,4-chloro-3-methylphenol 2,4-DCP, 2,4-dichlorophenol 2,4-DNP, 2,4-dinitrophenol 2,4,6-TCP, 2,4,6-trichlorophenol 2-M-4.6-DNP, 2-methyl-4,6-dinitrophenol and PCP, pentachlorophenol. Spike level 1 pg/L 10 mL preconcentrated. 

Sintox 9 mm Luger Brass Ni-plated brass (trace Fe) Lead core (trace Fe, Cu, Sb), brass (trace Fe) base cup, full brass-coated Fe jacket (trace Al) NG, DPA, a phthalate plasticizer (trace DNT and a nitro DPA) K, Ca (trace S) also detected Zn, Ti (minor S, trace Cl, Al, Cu, Ca, Fe, K, Si, Na) dinitrophenol, a methyl propyl phenol, DPA, a phthalate plasticizer, a trace of DNT... 

HP. 223 5.56 CF Brass (trace Fe) Ni-plated brass Plastic core, full Fe jacket, copper coated NG, DPA, a phthalate plasticizer (trace DNT, EC, a nitro DPA) Ca, K, S, Cl also detected Sr (minor Ti, trace Cu, Ca, S, Zn, K, Fe) dinitrophenol, DPA, EC, A phthalate plasticizer (trace DNT, methyl propyl phenol)... 

Synonym(s) 4,6-Dinitro-ro-cresol 4,6-Dinitro-o-cresol DNOC DNC 3,5-dinitro-2-hydroxy-toluene, 2-methyl-4,6-dinitrophenol"... 

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