1- Methyl-2,4-dinitrobenzene

Choice of solvent for recrystallisation. Obtain small samples (about 0 5 g.) of the following compounds from the storeroom (i) salicylic acid, (Li) acetanilide, (iii) m-dinitrobenzene, (iv) naphthalene, and (v) p-toluene-sulphonamide. Use the following solvents distilled water, methylated spirit, rectified spirit, acetone, benzene and glacial acetic acid. 

Transfer the crude dinitrobenzene to a 250 ml. flask fitted with a reflux condenser, add 80-100 ml. of methylated (or rectified) spirit and heat on a water bath until all the crystalline solid dissolves. If the resulting solution is not quite clear, filter it through a fluted filter paper on a large funnel which has previously been warmed or through a warm Buchner funnel. Colourless crystals of m-dinitrobenzene (15 g.) are deposited on cooling. If the m.p. is below 89-90°, recrystaUisation is necessary. 

Rapid, simple, quaUtative methods suitable for determining the presence of benzene in the workplace or surroundings have been utilized since the 1930s. Many early tests offered methods for detection of aromatics but were not specific for benzene. A straightforward test allowing selective detection of benzene involves nitration of a sample to y -dinitrobenzene and reaction of the resultant ether extract with an ethanoHc solution of sodium hydroxide and methyl ethyl ketone (2-butanone), followed by the addition of acetic acid to eliminate interferences from toluene and xylenes. Benzene imparts a persistent red color to the solution (87). The method is claimed to be sensitive to concentrations as low as 0.27 ppm benzene from 10 mL air samples. 

Only 22-45% yields of m-fluoronitrobenzene are obtained from the fluoro-denitration of m dinitrobenzene by potassium fluoride in Af-methyl-2-pyrrolidone or hexamethylphosphoramide, along with significant amounts of 3,3 dinitro-diphenyl ether [107, 108, 109] (equation 32)... 

The action of hydroxylamine and sodium acetate in ethanol upon picryl chloride was stated to give 4,6-dinitrobenzofuroxan, and probably some of this compound was formed, although it was later shownthat much of the original work was faulty. A report that hydroxylamine and 2,4,5-trinitrotoluene give 5-methyl-6-nitro-benzofuroxan has been found to be incorrect. Benzofuroxan has not been prepared by V-oxidation of benzofurazan, and it seems unlikely that this could be achieved, since benzofuroxan itself is oxidizable by powerful reagents to o-dinitrobenzene (Section VI, B). A report of the oxidation by nitric acid of anthraceno[l,2-c]furazan to the furoxan is incorrectlv abstracted. 

Dimethylhydrazine Di methyl nitrosamine bis (Dimethylthiocarbamoyl) disulphide Dinitrobenzene (all isomers)... 

Potassium 4-chloro-3,5-dinitrobenzene-sulfonate, 31, 46 Potassium cyanate, 31, 9 Potassium cyanide, 30, 84 32, 31, 63 Potassium ethyl xanthate, 30, 56 Potassium hydroxide, 30, 103 Potassium iodide, 30, 34 31, 31, 66 Potassium methyl sulfate, 31, 73... 

Potassium 4-chloro-3,5-dinitrobenzene-sulfonate, 31, 46 Potassium cyanate, 31, 9 Potassium cyanide, 30,84 32,31,63 37,47 Potassium ethyl malonate, 37, 34 Potassium ethyl xanthate, 30, 56 Potassium fluoride, 36, 40 Potassium iodide, 30, 34 31, 31, 66 Potassium metal, 37, 29, 30 Potassium methyl sulfate, 31, 73 Potassium nitrate, 31, 46 Potassium 1-nitropropylnitronate, 37, 24 Potassium oxalate, 34, 83 Potassium permanganate, 30, 87 31, 59 Potassium sulfide, 32, 103 Potassium thiobenzoate, 32, 101 Potassium thiocyanate, 32, 39, 40 Prins reaction, 33, 72 Propane, 1, 3-dibromo-2, 2-Ws-(bromo-methyl)-, 31, 82... 

Bilikova and Kuthan [87] developed a gas chromatographic method for the determination of submicrogram concentrations of Carbofuran (2,3-dihydro-2, 2,-dimethylbenzofuran-7-yl-methyl carbamate) in soils. Soil samples are mixed with methanol-water (80 20) and water samples are extracted with chloroform. After separation of the chloroform, and weak alkaline hydrolysis, derivatization is performed with l-fluoro-2,4-dinitrobenzene. The ester produced is isolated from benzene and cleaned up with acetone. The acetone extract is used to determine Carbofuran by gas chromatography with a nitrogen-specific detector. 

Synonyms BRN 2052046 C-11008 CCRIS 1006 2,6-DNT 2,6-Dinitromethylbenzene 2,6-Dinitrotoluol 2,6-DNT EINECS 210-106-0 2-Methyl-l,3-dinitrobenzene RCRA waste number U106 UN 1600 UN 2038. 

Methyl-l,3-dinitrobenzene, see 2,6-Dinitrotoluene 2-Methyl-4,6-dinitrophenol, see 4,6-Dinitro-o-cresol 6-Methyl-2,4-dinitrophenol, see 4,6-Dinitro-o-cresol... 

Synonym Tricarbonyl Methylcyclopentane Methyldichlorosilane 1 -Methyl-2,4-Dinitrobenzene Methylene Chloride Methylene Dichloride Methylene Dimethyl Ether Methylenebis (4-Phenyl Isocyanate) Methyl Ether... 

Trialkylaryltin derivatives 30 are converted into fluoro-substituted derivatives 31. 37-38 (4-Mcth-oxyphenyl)trimethylsilane (32) in acetonitrile gives 4-fluoroanisole and (3-fluoro-4-meth-oxyphenyl)trimethylsilane in the ratio 1 2. A -Methyldiethanol esters of arylboronic acids 33 (l-aryl-5-methyl-2,8-dioxa-5-azonia-l-boranuidabicyclo[3.3.0]octanes) are converted into tluoroaromatic compounds with cesium fluoroxysulfate in acetonitrile in the presence of 1,3-dinitrobenzene at room temperature.39-40 Regiospecific synthesis of 2-fluoro-3-0-methyles-trone in 27 % yield occurs upon fluorination of the corresponding arylboronic acid with cesium fluoroxysulfate.41... 

Good yields of fluoro-substituted aromatics have been obtained when 1 -chloro-2,4-dinitrobenzene (10) and 1-chloro-2,6-dinitrobenzene (13) are first treated with pyridine or methyl-substituted pyridines to form intermediate salts 11 and 14 and then reacted with potassium fluoride in dimethylformamide or nitrobenzene to give the fluorides 12 and 15."°... 

Dinitrobenzene (5) has been converted to l-fluoro-3-nitrobenzene (6) with potassium fluoride in jV-methyl-2-pyrrolidone. Hexamethylphosphoramide can also be used as a solvent for this displacement reaction. Besides 5 some heterocyclic nitro compounds 7,9 were also converted to their respective fluoro analogs 8 and 10 by treating with potassium fluoride. 

Trinitro-3-methyl-diphenylamine or N-(2, 4 -DinitrophenylJ-4-nitro-m-toluidine, (0aN)aC6H3.NH.C8H3(CH3).N02 red prisms mp l7l-2c(from AcOH). Was obtained after a mixt of l-chloro-2,4-dinitrobenzene, 6-nitro-m-col ui dine and anhydrous AcONa had been heated for an hr at 190°... 

Tetranitro-N-methyl-diphenylamine or l-(21,4 - Dini tro-N-me thy lan ilino)-(2,4-dinitrobenzene), (OaN)iCsH3.N(CH3). C8H3-(NOa)a yel leafletsffrom ale or AcOH), mp 210° was prepd by nitrating 2,4-dinitro-N-methyl-diphenylamine as described in Ref 2. Its expt props were not examined... 

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