Chlorocarbonate, methyl

Chemical Designations - Synonyms Chlorocarbonic acid, methyl ester Chloroformic acid, methyl ester Methyl chlorocarbonate Chemical Formula CICOOCH3... 

Methyl carbitol, m73 4-Methylcatechol, d438 Methyl cellosolve, m71 Methyl cellosolve acetate, m75 Methyl chlorocarbonate, ml94 Methyl chloroform, t231... 

Methylbutyl Nitrite 3-Methylbutyraldehyde Methyl Carbitol Methyl Cellosolve Methyl Chloride Methyl Chlorocarbonate Methyl Chloroform Methyl Chlorofonnate... 

Methylcatechol, d389 Methyl Cellosolve, m65 Methyl Cellosolve acetate, m68 j8-Methylchalcone, d658 Methyl chlorocarbonate, ml 87... 

Methyl chlorocarbonate Formic acid, chloro-, methyl ester (8) Carbonochloridlc acid, methyl ester (9) (79-22-1) letraethylammonlum p-toluenesulfonate Ammonium, tetraethyl-, p-toluenesulfonate (8) Ethanammium, N,N,N-triethyl-, salt with 4-methylbenzenesulfonic acid (1 1) (9) (733-44-8)... 

Bimetallated compound 199, derived from thioanisole, reacts with 2 molar equiv of methyl chlorocarbonate to give the diester 200, which is converted into benzothiophene 201 (Scheme 39) <2002T4529>. 

Access to enantiopure oxazolidinones was afforded by treatment of the corresponding aziridines 207 or 209 with phosgene or methyl chlorocarbonate <03JOC104,03JOC43>. 

METHYL-2-CHLOROBENZEXE see CLKIOO METHYL CHLOROCARBONATE see MIGOOO METHYL(2-CHLOROETHYL)NITROSAMINEsee CIQ500... 

Methyl Allophanate. Three hundred five milliliters of methyl chlorocarbonate (4.0 mols) and 480 g. of finely powdered urea (8.0 mols) are placed in a 2-1. standard-taper round-bottomed flask equipped with a 60-cm. reflux condenser. The mixture is heated on a steam bath for 90 minutes. Four hundred milliliters of water is added to the warm reaction cake to decompose any unreacted chlorocarbonic ester and to remove by solution both unchanged urea and urea hydrochloride, t Methyl allophanate remains behind as a relatively water-insoluble residue. The suspension is filtered and the white product washed with three 250-ml. portions of water, then with 95% ethanol (two 250-ml. portions), and finally with 500 ml. of ethyl ether. It is air-dried. The yield of product will vary from 227 to 274 g. (48 to 58%). The product thus obtained is pure enough to use as the starting material for other reactions. It can be further purified by recrystallization from hot water using 27.5 ml. of water per gram of compound (85% recovery m.p. 215 to 216° with decomposition). 

The monosilyl alcohol, prepared as described earlier, is mctalatcd with hexane-free butyl-lithium in diethyl ether in the presence of Af,.V,lV,jV -tetramethylethylenediamine. The soluble dianion is then quenched with trimethylchlorosilane to give, on aqueous sulfuric acid hydrolysis, the alcohol as a 95 5 mixture of ZjE geometrical isomers. This is then converted to the acetate according to standard procedures or to the carbonate with methyl chlorocarbonate. 

METHYL CHLOROCARBONATE (79-22-1) Forms explosive mixture with air (flash point 54°F/12°C). Reacts with moisture in air, forming hydrogen chloride fumes. Reacts slowly with water or steam, forming hydrochloric acid, carbon dioxide gas, and methanol. Violent reaction with alkali metals, dialkylzincs, dimethyl formamide, dimethyl sulfoxide, ethers, ethylene glycol diethyl ether, strong oxidizers. Incompatible with strong bases, alcohols. Corrodes metals in the presence of moisture. Attacks some plastics, rubber, and coatings. 

Methyl Chlorocarbonate. Carbonochloridic acid methyl ester methyl chloroformate. C2H3C10, mol wt 94.50. C 25 42%. H 3.20%. Cl 37.52%, O 33.86%. CICO,-CHj. Made from phosgene and methyl alcohol. 

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