1- Methyl-1- ethyl carbamates

C21H21N3O9 4199-35-3) see Minocycline (/ )-[2-(dimethylamino)-2-oxo-l-[(phenylthio)methyl] ethyl]carbamic acid phenylmethyl ester (C,9H22N20iS 197302-34-4) see Nelfinavir mesylate lV-[3-[3-(dimethylamino)-l-oxo-2-propenylJphenyl]acet-amide... 

Methyl Carbamate 5. 9-Fluorenylmethyl Carbamate 8. 2,2,2-Trichloroethyl Carbamate 11. 2-Trimethylsilylethyl Carbamate 16. 1,1-Dimethylpropynyl Carbamate 20. 1-Methyl-1-phenylethyI Carbamate 22. 1-Methyl-l-(4-biphenylyl)ethyl Carbamate 24. 1,1 -Dimethy 1-2-haloethyl Carbamate 26. l,l-Dimethyl-2-cyanoethyl Carbamate 28. r-Butyl Carbamate... 

A. Ethyl N- p-tolylsulfonylmethyl)carhamate,[Carbamic acid, (4 -methyl-phenylsulfonylmethyl)-, ethyl ester]. A solution of 178 g. (1.0 mole) of sodium p-toluenesulfinate (Note 1) in 1 1. of water is placed in a 3-1., three-necked daak, equipped with a condenser, an efficient mechanical stirrer, and a thermometer. After addition of 100 ml. (108 g.) of a 34—37% solution of formaldehyde ca. 1.2-1.4 moles) (Note 2), 107 g. (1.2 moles) of ethyl carbamate (Note 3), and 250 ml. of formic acid (Note 4), the stirred solution is heated to 70°. Soon after this temperature is reached, the reaction mixture becomes turbid by separation of the... 

We have investigated Ce(IV) ion-carbamates, such as methyl and butyl 4-methylphenyl-carbamate, (MTC and BTC, respectively), or methyl, ethyl, and butyl phenylcarbamate, (MFC, EPC and BPC, respectively), systems for AAM polymerization [19]. It was found that the presence of carbamate compounds can promote the polymerization and enhance the rate of AAM polymerization (Rp) in descending order as ... 

Methyl ether cleavage, 59, 39 Methyl cw-M(l-ethoxy-2,3-dimethyl-cyclopropyl)carbamate, 59,138 Methyl rrans-A -(l-ethoxy-2,3-dimethyl-cyclopropyl)carbamate, 59, 138 Methyl ethyl ketone, 55, 25 5 -Methyl ferrocenethiocarbonate, 56, 30 Methyl formate, 59, 183 Methyl fumarate, 56, 63... 

This intermediate (or its ethyl homologue), produced dining the preparation of phosphoryl dichloride isocyanate from interaction of phosphorus pentachloride and methyl (or ethyl) carbamate, is unstable. Its decomposition to the required product may be violent or explosive unless moderated by presence of a halogenated solvent. 

To verify such a steric effect a quantitative structure-property relationship study (QSPR) on a series of distinct solute-selector pairs, namely various DNB-amino acid/quinine carbamate CSPpairs with different carbamate residues (Rso) and distinct amino acid residues (Rsa), has been set up [59], To provide a quantitative measure of the effect of the steric bulkiness on the separation factors within this solute-selector series, a-values were correlated by multiple linear and nonlinear regression analysis with the Taft s steric parameter Es that represents a quantitative estimation of the steric bulkiness of a substituent (Note s,sa indicates the independent variable describing the bulkiness of the amino acid residue and i s.so that of the carbamate residue). For example, the steric bulkiness increases in the order methyl < ethyl < n-propyl < n-butyl < i-propyl < cyclohexyl < -butyl < iec.-butyl < t-butyl < 1-adamantyl < phenyl < trityl and simultaneously, the s drops from -1.24 to -6.03. In other words, the smaller the Es, the more bulky is the substituent. The obtained QSPR equation reads as follows ... 

Protonation studies of methyl tmd ethyl carbamate [123] and their N-methyl and N,N-dimethyl derivatives (Armstrong and... 

Acetyluracil — Ethyl 2-hydroxy-4-methyl-5-pyrimidinecarboxylate (XXXVI), which is prepared by the cyclization of the ureidomethylene derivative of aceto-acetic ester, can be caused to rearrange into 5-acetyluracil (XXXVII) in dilute alkali [304]. Compound (XXXVII) can also be prepared from diketene and ethyl carbamate, followed by treatment with ethyl orthoformate and cyclization with ammonia [305]. 

Compounds in this dibenzocycloheptene series also manifest antidepressant activity when the trigonal one-carbon bridge is replaced by tetrahedral carbon. Thus, the reaction of hydrocarbon (24-7) with a metal amide in liquid ammonia leads to the corresponding carbanion (29-1). Treatment of that with the ethyl carbamate from A -methyl-3-chloropropylamine (29-2) leads to the alkylation product. The carbamate protecting group is then removed by sequential saponification with a base followed by acidification. This yields the antidepressant agent protriptyline (29-3) [30]. 

The reaction of primary alcohols with urea gives carbamates when the reaction is carried out at 115°-l 50°C [7-10] (Eqs. 2, 3). Since 150°C is the temperature for the optimum dissociation of urea to cyanic acid and ammonia, lower-boiling alcohols (methyl, ethyl, and propyl) must be heated under pressure. Refluxing urea and n-butanol at 115°-120°C requires a 40-hr reaction time to... 

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