Metacresol

Metacresol purple, m-cresol-sulfonphthalein (indicator) dissolveO.l g in 13.6 mL 0.02A NaOH and dilute with water to 250 mL acid pH range red 0.5-2.5 yellow, alkaline pH range yellow 7.4-9.0 purple. 

Metacresol purple is an indicator that changes from yellow to purple at pH 8.2. 

Sulphonphthaleins. These indicators are usually supplied in the acid form. They are rendered water-soluble by adding sufficient sodium hydroxide to neutralise the sulphonic acid group. One gram of the indicator is triturated in a clean glass mortar with the appropriate quantity of 0.1 M sodium hydroxide solution, and then diluted with water to 1 L. The following volumes of 0.1 M sodium hydroxide are required for 1 g of the indicators bromophenol blue, 15.0 mL bromocresol green, 14.4 mL bromocresol purple, 18.6 mL chlorophenol red, 23.6 mL bromothymol blue, 16.0 mL phenol red, 28.4 mL thymol blue, 21.5 mL cresol red, 26.2 mL metacresol purple, 26.2 mL. 

Balanced equation HIn + H20 H30+ + In-, where metacresol purple is represented by HIn... 

The unfolding behavior of multidomain proteins in the presence of preservatives has also been evaluated. For example, IL-1R (type I) has three domains that correspond to three unfolding transitions as measured by microcalorimetry and depicted in Figure 13.1.31 All three transitions exhibit some shift to lower Tm in the presence of the three preservatives tested (i.e., 0.065% phenol, 0.1% metacresol, and 0.9% benzyl alcohol), in comparison to a control containing no preservative. Such a destabilization could have consequences for the shelf-life of the product. Another example of the impact of preservatives on a multidomain protein is illustrated in Figure 13.5. The protein is fused to a single IgCi, Fc. The... 

The behaviour with organic materials is generally good, except for alkaline products (amines, for example) and certain specific chemicals such as metacresol and hot nitrobenzene, which cause significant swelling (75-85%, for example). 

Known hypersensitivity to pramlintide acetate or any of its components, including metacresol diagnosis of gastroparesis hypoglycemia. 

Cresol red Crystal Violet Malachite Green Methanil Yellow Thymol Blue Orange IV -2,4-Dinitrophenol -Erythrosin, Na2 salt -Dimethyl Yellow Cl 11020 Bromophenol Blue Congo Red Cl 22120 Methyl Orange Bromocresol Green Alizarin Red S Cl 42750 Methyl Red Cl 13020 -Bromocresol Purple Chlorophenol Red p-Nitrophenol Alizarin Bromothymol Blue Brillant Yellow Phenol Red Neutral Red Cl 50040 -m-NItrophenol -Cresol Red Metacresol Purple Phenolphthalein -Thymolphthalein -P-Naphthyl Violet Alizarin Yellow R 2,4,6-T rinitrotoluene... 

For example, PBLG molecules have a persistence length of around 120 nm (Jackson and Shaw 1991 Ookubo et al. 1976) in the solvent metacresol and a diameter J of 1.54 nm, so that the aspect ratio kp fd of a single persistence length of the molecule is around 78. According to the Semenov-Khokhlov theory, for long PBLG molecules the phase transition to a nematic should occur at a polymer volume fraction of 02 0.073, not far from the experimental value of around 0.080. Further details can be found in Sato and Teramoto (1996). 

McSherry TJ. Incompatibility between chlorpromazine and metacresol [letter]. Am ] Hasp Pharm 1987 44 1574. 

Addo trimico 3-p-cymenol p-cymen-3-ol Flavinol 3-hydroxy-p-cymene 3-hydroxy-l-methyl-4-isopropylbenzene Intrasol isopropyl cresol isopropyl-w-cresol 6-isopropyl-m-cresol isopropyl metacresol 2-isopropyl-5-methylphenol 1-methyl-3-hydroxy-4-isopropylbenzene 5-methyl-2-isopropyl-phenol 5-methyl-2-(l-methylethyl) phenol Medophyll thyme camphor thymic acid m-thymol timol. 

Phenol is used for the manufacture of picric acid. Metacresol can be similarly converted to trinitrometacresol. Technical metacresol contains ortho- and paracrcsol. On nitration these isomers are oxidised to oxalic acid. An approximate estimate of the content of metacresol can be obtained by a trial nitration under definite... 

Metacresol Purple R 9cl Orange i j Yellpw j i Grey Violet ... 

The indicator metacresol purple changes from yellow to purple at pH 8.2. At this point it exists in equal concentrations as the conjugate acid and the conjugate base. What are and p for metacresol purple, a weak acid represented as HIn ... 

Metacresol Parabens (Hydroxybenzoates Methyl, Propyl) Phenol... 

The largest commercial organic phosphate esters then on the market were tricresyl and triphenyl phosphate. Both of these esters were produced by the reaction of phosphorus oxychloride with the phenol or the cresol, usually as a mixture of para- and metacresol (equations 4,5). 

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