O-isopropyl phenol

SYNS 2-ISOPROP T.PHENOL 2-(l-METHYLETHYL)PHENOL PHENOL, o-ISOPROPYL- PHENOL, 2-(l-METHYLETHYL)-(9CI) PRODOX 131... 

Boron trifluoride catalyzes the condensation of phenol and propylene to isopropyl phenyl ether and the subsequent rearrangement of this compound to o-isopropyl phenol. This rearrangement of an aryl alkyl ether is similar to the Fries reaction of phenolic esters (method 209). 

Synonyms o-Cumenol 2-Hydroxycumene 2-Isopropylphenol 2-(1-Methylethyl) phenol OIP OIPP Phenol, o-isopropyl- Phenol, 2-(1-methylethyl)-... 

The FTIR spectra of the gas mixture evolved in thermal decomposition of Bisphenol AF poly(formal) (7) at various temperatures suggest the existence of benzene rings, C—O—C bonds, and C=C bonds. In a pyrogram of pyrolysis gas chromatography (Py-GC) of Bisphenol A (3), a-methylstyrene, phenol, p-cresol, 4-hydroxy-amethylstyrene, and isopropyl phenol are observed as major peak products. The cleavage reactions shown in Scheme (5) is suggested for the formation of phenol and 4-hydroxy-a-methylstyrene from Bisphenol A (3). 

Methylation of alkaloids containing either phenolic hydroxy groups or secondary amine functions is the most common procedure for converting such alkaloids to known derivatives many examples are given in Section II,C. Diazomethane is the reagent of choice for O-methylation, and diazoethane for O-ethylation. It is possible to effect O-alkylation in the presence of secondary amine functions, as in the conversion of peinamine to its trideuteriomethyl ether (Section II,C,92) and of A-desmethylthalrugosidine to the O-ethyl ether (Section II,C,29). Another O-alkylation method, exemplified by the preparation of O-methyl, O-ethyl, and O-isopropyl ethers of berbamine (364), consisted of heating the alkaloid in... 

SYNS BAY 39731 BAY 105807 BAYER 39731 CARBAMIC ACID, METHYL-, o-ISOPROPYLPHENYL ESTER CARBAMIC ACID, METHYL-, 2-(l-METHYI ETHYL)PHEKYL ESTER o-CUMENYL METHYL-CARBAMATE ENT 25,670 ETROFOLAN D HYTOX ISOPROCARB ISOPROCARBE o-ISOPROPYI PHENOL METHYLCARBA L TE o-ISOPROPYLPHENYL N-METHYLCARBAMATE 2-ISOPROPYL-PHENYL N-METHYLCYRBAMATE KHE0145 2-(l-... 

Synonyms Carbamic acid, methyl-, o-isopropy I phenyl ester Carbamic acid, methyl-, 2-(1-methylethyl) phenyl ester o-Cumenyl methylcarbamate Isoprocarb o-Isopropylphenol methylcarbamate o-lsopropylphenyl N-methylcarbamate Methyl carbamic acid-o-cumenyl ester 2-(1-Methylethyl) phenyl methylcarbamate MIPC Phenol, o-isopropyl-, methylcarbamate Phenol, 2-(1-methylethyl)-, methylcarbamate Empiricai C11H15NO2... 

Phenol, o-isopropyl-. See o-lsopropylphenol Phenol, p-isopropyl. See p-lsopropylphenol Phenol, 4,4 -isopropylldenedl-. See Bisphenol A Phenol, 4,4 -isopropylidenedi-, polymer with 1-chloro-2,3-epoxypropane. See poxy, bisphenol A/epichlorohydrin Bisphenol A/epichlorohydrin resin... 

Phenol, o-isopropyl-, methylcarbamate. See 2-Isopropylphenyl N-methylcarbamate Phenol, liquefied. See Phenol Phenol, 4-methoxy-. See Hydroquinone monomethyl ether... 

The reaction is accompanied with the cleavage of O-isopropyl protecting group, which occured after addition of methanol. Anhydrous iron(lll) chloride efficiently affects the room temperature oxidative coupling reactions of electron-rich aromatics other than phenols and phenol-ethers, e.g. thiophenes [39], as well as the cross-eouplings, e.g. A-alkylcarbazoles with pyridine-A -oxides [40], ete. 

In a pyrogram of Bisphenol A poly(formal) (6), the peak products are identified as a-methylstyrene, phenol, 4-hydroxy-a-methylstyrene, and isopropyl phenol by Py-GC/MS. These products are identical with the degradation products from Bisphenol A. In addition to the decomposition products of Bisphenol A, 4-isopropenyl anisole is also identified as a product. The pyrograms of Bisphenol AF poly(formal) (7) contain only two major species, pentafluoroisopropenyl benzene (product T) and pentafluoroisopropenyl anisole (product 2 ). They correspond to o-methylstyiene, 4-hydroxy-06-methylstyrene from Bisphenol A poly(formal) (6) and are produced by the cleavage of phenylene-oxy bonds and oxy-methylene bonds according to (Scheme 6). 

Takacs [85] has separated the o- and p-benzoquinol acetates and o-quinone diacetate resulting from oxidation with lead tetraacetate of phenols containing an o-isopropyl, sec-butyl or tert.-butyl group. The o-derivatives were separated and purified on silica gel G. A 1 % solution of p-dimethylaminobenzaldehyde in concentrated sulphuric acid was... 

Based on analysis of products distribution [25], it was concluded that there were two kinds of decomposition action hydrolysis mainly at lower temperature and pyrolysis mainly at higher temperature. At low-temperature stage, the brominated epoxy resin was mainly decomposed into bisphenol A, brome-phenol, isopropyl phenol monomer, etc., while at high-temperature stage, the brominated epoxy resin was mainly decomposed into phenol, o-cresol, p-cresol, and other small molecule compormds without bromine. 

Physostigmine can be regarded as the methylcarbamate of a -amino-phenol, with an alkyl chain substituent in the o-position, relative to the amino-group. Stevens and Beutel, with this in mind, have prepared substances of the type p-RjRjjN, CO, O. CgHjR. NMCjX, where R is an alkyl radical, c.gi, isopropyl, in either the o or m-positioQ relative to the... 

Following the successful demonstration of an enamine photocyclization, Ninomiya synthesized ( )-cryptaustoline iodide from 44b. Irradiation of isopropyl ether 44b gave a mixture of dibenzopyrrocolines 45b and 45c in 12 and 11% yield, respectively. The isopropyl ether group in 45c was selectively hydrolyzed by hydrobromic acid, and the resulting phenolic compound was converted to cryptaustoline iodide with methyl iodide. An attempt to photocyclize an O-benzyl ether analog of 44b was less satisfactory. 

To be effective as autoxidation inhibitors radical scavengers must react quickly with peroxyl or alkyl radicals and lead thereby to the formation of unreactive products. Phenols substituted with electron-donating substituents have relatively low O-H bond dissociation enthalpies (Table 3.1 even lower than arene-bound isopropyl groups [68]), and yield, on hydrogen abstraction, stable phenoxyl radicals which no longer sustain the radical chain reaction. The phenols should not be too electron-rich, however, because this could lead to excessive air-sensitivity of the phenol, i.e. to rapid oxidation of the phenol via SET to oxygen (see next section). Scheme 3.17 shows a selection of radical scavengers which have proved suitable for inhibition of autoxidation processes (and radical-mediated polymerization). 

Regioselective substitution reactions of a series of 2- and 3-hydroxybiaryls including BINOL have been performed via a new directed orf/io-metallation procedure.75 O-Aryl AMsopropylcarbamates, conveniently prepared from phenols and isopropyl isocyanate, have been temporarily and in situ N-protected by means of silyl inflates to form stable intermediates for low-temperature lithiation reactions using n-BuLi-TMEDA in diethyl ether. The IV,IV-dialkyl aryl O-sulfamate has been reported as a new directed metallation group.76... 

Fig (4) The transformation of the ketone (24) to the cyclic ether (9) applying the standard organic reactions is described It wa subjected to three sequencial reactions with reagents mentioned for the conversion to cyclic ether (30). Isopropylation and by aromatization, it produces the phenol (31), which is converted to pisiferol (4). This on subjection to oxidation, esterification and deoxygenation respectively, furnish O-methyl pisiferate (5) and this is easily converted to pisiferic acid (1). 

METHYLETHYL)PHENYL METHYLCARBAMATE O MIPC MIPCIN MIPCINE MIPSIN OMS-32 PHENOL, 0-ISOPROPYL-, METHYLCARBAMATE PHENOL, 2-(l-METHYLETHYL)-, METHYLCARBAMATE (9CI) PPC 3 RO 7-5050... 

DICHLORO-PHENOL-O-ESTER with 0,0-DIETHYL PHOSPHOROTHIOATE see DFK600 (2,4-DICHLOROPHENOXY)ACETIC ACID, ISOPROPYL ESTER see lOYOOO (2-4-DICHLOROPHENOXY)ACETIC ACID-1-METHYLETHYL ESTER (9CI) see lOYOOO... 

O-Aryl-A X-dicyclohexylisoureas are synthesized by stirring mixtures of phenols with 2-3 mol equiv. of dicyclohexylcarbodiimide at 45-100 C for 1-3 d. Hydrogenations are accomplished in isopropyl alcohol or ethyl acetate at 20 °C and atmospheric pressure using 200-300 mg of 5% palladium on carbon or on calcium carbonate per 0.02 mol of the phenol. The hydrogenolysis can also be effected with the crude mixture of the O-arylisoureas and the unreacted carlx iimide using as much hydrogen as needed for hydrogenation of the excess carbodiimide. 

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