Metabolite fingerprints

The lipidome profile of mice liver homogenates of free cholesterol, low cholesterol, and high cholesterol diets showed the influence between dietary cholesterol intake and atherosclerosis (17). To get individual metabolite fingerprints, they measured near 300 metabolites such as di- and triglycerides, phosphatidylcholines, LPCs, and cholesterol esters in plasma samples by LC-MS/MS. It was observed that when dietary cholesterol intake was increased, the liver compensated for elevations in plasma cholesterol by adjusting metabolic and transport processes related to lipid metabolism, which... 

Metabolic profding and metabolite fingerprinting approaches require a sensitive full scan mode and exact masses. Therefore, Q40F or Qrtrap-FT-ICR MS instruments are advantageous. In contrast, for targeted... 

Lightfoot Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene J. Biomed. Biotechnol. 2 2667g. 

Beckmann, M., Parker, D., Enot, D. R, Duval, E., and Draper, J. 2008. High-throughput, nontargeted metabolite fingerprinting using nominal mass flow injection electrospray mass spectrometry. Nat. Protoc. 3 486-504. 

Beckmann M, et al. High-throughput, nontargeted metabolite fingerprinting using nominal mass flow injection electrospray mass spectrometry. Nature Protocols... 

P. Scano, etal., H-1 NMR metabolite fingerprinting as a New tool for body fluid identification in forensic science, Magn. Reson. Chem. 51 (2013) 454—462. 

Fotakis, C.H., Christodouleas, D., Kokkotou, K., Zoumpoulakis, P., and Zervou, M. 2013b. NMR metabolite fingerprinting in grape derived products An review Food Research International. 54 1184-1194. 

Ward JL, Harris C, Lewis J, Beale MH (2003) Assessment of H NMR spectroscopy and multivariate analysis as a technique for metabolite fingerprinting of Arabidopsis. Phytochemistry 62 949-957... 

Control of flowering time by FLC orthologues in Brassica napus. Plant J. 28, 545-553. Tsogtbaatar, E., Cocuron, J.C., Sonera, M.C., Alonso, A.P., 2015. Metabolite fingerprinting of pennycress Thlaspi arvense L.) embryos to assess active pathways during oil synthesis. J. Exp. Bot. 66, 4267-4277. 

---