Map, metabolic

H. Aizawa, Metabolic Maps of Pesticides, Academic Press, Inc., New York, 1982. 

FIGURE 1.20 Rep roduction of a metabolic map. (Courtesy ofD. E. Nicholson, University of Leeds anel Sigma Chemical Co., St. Louis, MO.)... 

FIGURE 18.2 The metabolic map as a set of dots and lines. The heavy dots and lines trace the central energy-releasing pathways known as glycolysis and the citric acid cycle. 

Number of Dots (Intermediates) in the Metabolic Map of Figure 18.2, and the Number of Lines Associated ... 

Sagar, S. M Sharp, F. R. Curran, T. (1988). Expression of c-fos protein in brain metabolic mapping at the cellular level. Science 240, 1328-31. 

Pathways can be illustrated in a metabolic map as linear, branched or cyclic processes (Figure 1.3) and are often compartmentalized within particular subcellular location glycolysis in the cytosol and the Krebs tricarboxylic acid (TCA) cycle in... 

Reactions operating far from their equilibrium position are not easy to identify merely by looking at the metabolic map, although the involvement of ATP is often a significant clue to a reaction being irreversible. Stated simply, hydrolysis of ATP energizes a reaction which is normally irreversible. However, we can often predict the existence of... 

Like glucose-6-P, pyruvate and acetyl-CoA are at metabolic cross-roads. Consult a metabolic map and identify these important compounds and note the ways in which they may be formed and metabolized. 

S. Smesny, T. Rosburg I. Nenadic, et ah. Metabolic mapping using 2D P-MR spectroscopy reveals frontal and thalamic metabolic abnormalities in schizophrenia. Neuroimage, 2007, 35, 729-737. 

Figure 3.1. Anyone learning biochemistry is introduced to metabolic maps of the type shown here. These 2-D representations of major pathways are becoming increasingly misleading because as this chapter shows the majority of enzymatic transformations in the natural world do not stick to the simple rules implied by such a map. The great majority of chemical diversity made by organisms is made by enzymes that are much more multifunctional so they are less easily placed on a simple 2-D map.

AizawaH. 1989. Metabolic maps of pesticides. Vol. 2. Ecotoxicology and Environmental Quality Series. Academic Press, Inc. 161. 

The Absolute, Ultimate Guide combines an innovative study guide with a reliable solutions manual in one convenient volume. A poster-size Cellular Metabolic Map is packaged with the Guide, on which students can draw the reactions and pathways of metabolism in their proper compartments within the cell. 

The tricarboxylic acid cycle shown as a part of the central pathways of energy metabolism. (See Figure 8.2, p. 90 for a more detailed view of the metabolic map.)... 

Hexose monophosphate pathway shown as a component of the metabolic map (see Figure 8.2,... 

Straub, K. M. Rudewicz, P. Garvie, C. 1987. Metabolic mapping of drugs rapid screening techniques for xenobiotic metabolites with m.s./m.s. techniques. Xenobiotica,17, 413-422. 

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