Medicines Doxorubicin

The NDA law (safety and effectiveness) applies to all drugs, but antibiotic drugs were treated differently until the passage of FDAMA in 1997. Antibiotic drugs had been treated differently by the FDA since the development of penicillin revolutionized medicine during World War II. The laws applicable to antibiotic drugs were covered in 21 CFR 430 and 431. Antibiotics such as penicillin or doxorubicin are... 

Doxorubicin hydrochloride (Ph. Eur. Reference standard) from the European Directorate for the Quality of Medicine and Healthcare (Council of Europe), Strasbourg, France. Store at -20 °C. 

F. Arcamone, Doxorubicin Anticancer Antibiotics, Medicinal Chemistry Monograph, Vol. 17, Academic Press, New York, 1981. 

Angelucci F, Ballinari D, Farao M. Synthesis and biological evaluation of polymer-bound 3 -deamino-3 [2(S)-methoxy-4-morpholinyl] doxorubicin. Proceedings of the Xlll International Symposium on Medicinal Chemistry, Paris 1994. 

Arcamone F (1981) In Stevens G (ed) Doxorubicin anticancer antibiotics. Medicinal chemistry series of monographs, vol 17. Academic, New York... 

Al-Omar, A., Abdou, S., De Robertis, L., Marsura, A., and Finance, C. (1999). Complexation study and anticel-lular activity enhancement by doxorubicin-cyclodextrin complexes on a multidrug-resistant adenocarcinoma cell line. Bioorganic and Medicinal Chemistry Letters, 9, 1115-1120. 

Du, L., Jin, Y, Zhou, W., Zhao, J. (2011). Ultrasound-triggered drug release and enhanced anticancer effect of doxorubicin-loaded poly(D,L-lactide-co-glycolide)-methoxy-poly (ethylene glycol) nanodroplets. Ultrasound in Medicine Biology, 57(8), 1252-1258. 

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