Poly doxorubicin-loaded

PolyDOX Doxorubicin-loaded hyaluronan-h/oc -poly( y-benzyl glutamate) vesicle PSar Poly(sarcosine)... [Pg.118]

Upadhyay KK, Bhatt AN, Mishra AK, Dwarakanath BS, Jain S, Schatz C, Le Meins JE, Earooque A, Chandraiah G, Jain AK, Misra A, Lecommandoux S (2010) The intracellular drug delivery and anti tumor activity of doxorubicin loaded poly(y-benzyl L-glutamate)-b-hyaluronan polymersomes. Biomaterials 31(10) 2882... [Pg.134]

Kataoka K, Matsumoto T, Yokoyama M et al (2000) Doxorubicin-loaded poly(ethylene glycol)-poly(P-benzyl-L-aspartate) copolymer micelles their pharmaceutical characteristics and biological significance. J Control Release 64 143-153... [Pg.58]

The superiority of doxorubicin targeted with the aid of poly(alkylcyanoacrylate) nanospheres was later confirmed in a murine hepatic metastases model (M5076 reticulosarcoma). Irrespective of the dose and the administration schedule, the reduction in the number of metastases was much greater with doxorubicin-loaded nanospheres than with free doxorubicin, particularly if treatment was given only when the metastases were... [Pg.1191]

Ambruosi A, Khalansky AS, Yamamoto H et al (2(X)6) Biodistribution of polysorbate 80-coated doxorubicin-loaded [14C]-poly(butyl cyanoacrylate) nanoparticles after intravenous administration to gUoblastoma-bearing rats. J Drug Target 14 97-105... [Pg.228]

A. Ambruosi et al, Influence of surfactants, polymer and doxorubicin loading on the anti-tumour effect of poly(butyl cyanoacrylate) nanoparticles in a rat glioma model. /. Microencapsul, 23(5), 582-592 (2006). [Pg.578]

The most widely used hydrophilic sheddable group used to improve blood stability is PEG. However, sugars also have biofouling properties, and promising doxorubicin-loaded nanoparticles with reduction-induced detachment of the lactobionic acid shell have been recently reported [98]. Doxorubicin was loaded in poly(e-caprolactone)-graft-SS-lactobionic add (PCL-g-SS-LBA) nanoparticles capable of doxorubidn release after GSH treatment. [Pg.320]

Du, L., Jin, Y, Zhou, W., Zhao, J. (2011). Ultrasound-triggered drug release and enhanced anticancer effect of doxorubicin-loaded poly(D,L-lactide-co-glycolide)-methoxy-poly (ethylene glycol) nanodroplets. Ultrasound in Medicine Biology, 57(8), 1252-1258. [Pg.253]

Upadhyay KK, Le Meins J-F, Mishra AK, Voisin P, Bouchaud V, Ibarboure E, Schatz C, Lecommandoux S (2009) Biomimetic doxorubicin loaded polymersomes from hyaluronan-block-poly(gamma-benzyl glutamate) copolymers. Biomacromolecules 10(10) 2802-2808... [Pg.109]

Amjadi, I., Rabiee, M., Hosseini, M.S., Mozafari, M. Synthesis and characterization of doxorubicin-loaded poly(lactide-co-glycolide) nanoparticles as a sustained-release anticancer drug delivery system. Appl. Biochem. Biotechnol. 168, 1434-1447 (2012). doi 10.1007/ S12010-012-9868-4... [Pg.469]

Jaiswal M, Naz F, Dinda AK, Koul V (2013). In vitro and in vivo efficacy of doxorubicin loaded biodegradable semi-interpenetrating hydrogel implants of poly (acrylic acid)/gelatin for post surgical tumor treatment. Biomed Mater, 8,045004. [Pg.613]

Tewes, F. et al. Comparative study of doxorubicin-loaded poly(lactide-co-glycoUde) nanoparticles prepared by single and double emulsion methods. European Journal of Pharmaceutics and Biopharmaceutics 66,488-492,2007. [Pg.1685]

Haiqing Yin You Han Bae. Physicochemical aspects of doxorubicin-loaded pH-sensitive polymeric micelle formulations from a mixture of poly(L-histidine)-b-poly(L-lactide)-b-poly(ethylene glycol). European Journal of Pharmaceutics and Biopharmaceutics, doi 10.1016/j.ejpb.2008.08.013... [Pg.1465]

For example, surfaces comprising PNIPAM microgels were utilized for drug delivery [138], Electrostatic layer-by-layer assembly with poly(NIPAM-coacrylic acid) and poly(allylamine hydrochloride) on an amino-functionalized surface yielded thermoresponsive thin films. These were capable of a thermally regulated uptake and release of the chemotherapeutic drug doxorubicin. The films were loaded... [Pg.17]

Poly(alkyl cyanoacrylate) nanoparticles accumulate in the liver (60-90% of the injected dose) and the spleen upon iv injection, with the macrophages in the liver being their major target. Nanoparticles loaded with doxorubicin have shown a markedly enhanced therapeutic index in a number of animal tumor models. [Pg.124]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...