Mechanism infiltration theory

A number of mechanisms have been suggested to explain the process of tumor cell invasion in terms of observed properties of neoplastic cells. One of these, that tumor invasion is the result of cellular multiplication and mechanical expansion, visualizes tumor infiltration as resembling the growth of a plant root. According to this theory, the pressure from a constantly increasing cell mass is thought to cause... 

The current concept of atherosclerosis fonnation postulates that arterial injury occurs first followed by a sequence of events culminating in plaque deposits. The two prevalent theories of plaque pathogenesis are the infiltration concept and the thrombogenic theory. They involve different mechanisms and are not easily reconcilable. The filtration theory presumes that the plasma constituents which normally diffuse into the vessel wall from the luminal surface are localized at the injury site initiating plaque formation. In the other major theory, mural thrombi adhere to the injury surface and become incorporated into the wall by an overgrowth of endothelium. The type of plaque formed is dependent upon the ratio of the adhering materials, platelets and fibrin. 

---