Mechanical properties and degradation

Raynaud S, Champion E, Bemache-Assolant D (2002b) Calcium phosphate apatites with variable Ca/P atomic ratio II. Calcination and Sintering. Biomaterials 23 1073-1080 Raynaud S, Champion E, Lafon JP, Bemache-Assolant D (2002c) Calcium phosphate apatites with variable Ca/P atomic ratio III. Mechanical properties and degradation in solution of hot pressed ceramics. Biomaterials 23 1081-1089... 

Broadly speaking, biomaterials used as supporting matrix for tissue repair applications must meet two requirements mechanical and structural similarity to the target tissues, and appropriate interactions with cells [5]. Synthetic biopolymers have attracted much attention because they display mechanical properties and degradation behaviors more suitable for some applications than their natural counterparts mentioned above. However, the synthetic biopolymers have disadvantages such as hydrophobicity and poor cell affinity as well as lack of biological responses [81]. It is a simple but effective strategy to combine synthetic biopolymers with... 

Cheng Mei-Ling, Chen Po-Ya, Lan Chin-Hung, Sun Yi-Ming, Structure, mechanical properties and degradation behaviors of the electrospun fibrous blends of PHBHHx/ PDLLA. Polym. 2011, doi 10.1016/j.polymer.2011.01.039 in press. 

Only a few PHAs can be produced in the amounts needed for biomedical research [45,48,49], The composition of PHA can be readily changed, thus allowing the selection of mechanical properties and degradation time to meet the needs of very specific clinical applications [20,50], PHBs have been successfully used as films in cell cnltnre studies [51] and as microparticles that promoted ceU attachment. 

Cheng, Mei-Ling, Chen, Po-Ya., Lan Chin-Hung, Sun Yi-Ming. (2011). Structure, Mechanical Properties and Degradation Behaviors of the Electrospun Fibrous Blends of PHBHHx/PDLLA. Polymer, 52, 6587-6594. 

Mechanical properties and degradation of poly-e-caprolactone-based biomaterials... 

Table 3.3 Comparison of poly-e-caprolactone mechanical properties and degradation behaviour with other biomaterials...

By controlling the temperature and time of postpolymerization, the elastomer s mechanical properties and degradation rate can be tuned to fit a wide range of tissue-engineering applications. An increase in postpolymerization temperature and time resulted in a network with inaeased mechanical properties due to the increased cross-linking density. The introduction of CUPEs presents new avenues to meet the versatile requirements for tissue engineering and other biomedical applications. 

Collagen has been widely studied for biomedical applications such as bioresorbable sutures, artificial skin, wound dressings, and vascular grafts, due to its biocompatibility, mechanical properties, and degradability by enzymes like... 

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