Measuring Bioreactor Hydrodynamic Characteristics

Hydrodynamics in gas-liquid systems have been studied extensively in the past due to their wide range of applications. Characteristics of interest include flow regimes, local pressure drop, gas residence time, axial diffusion coefficients, bubble size, bubble rise velocity, gas holdup, and power consumption. This section will summarize various experimental techniques to quantify some of these characteristics. [Pg.17]

An Introduction to Bioreactor Hydrodynamics and Gas-Liquid Mass Transfer, First Edition. Enes Kadic and Theodore J. Heindel. [Pg.17]

Williams, 1996 Boyer et al 2002 Ceccio and George, 1996 Chaouki et al., 1996, 1997 Cheremisinoff, 1986 Heindel, 2011 Hewitt, 1978,1982 Kumar etal., 1997 Mudde, 2010a Powell, 2008 Prasser, 2008 Vatanakul etal., 2004 Vial etal., 2003 Williams and Beck, 1995). [Pg.18]

MEASURING BIOREACTOR HYDRODYNAMIC CHARACTERISTICS 29 Stirred-tank reactor... [Pg.29]

A significant difficulty in characterizing and quantifying gas-liquid, liquid-solid, and gas-liquid-solid mixtures commonly found in bioreactor flows is that the systems are typically opaque (e.g., even an air-water system becomes opaque at fairly low volumetric gas fractions) this necessitates the use of specially designed invasive measurement probes or noninvasive techniques when determining internal flow and transport characteristics. Many of these probes or techniques were developed for a particular type of gas-liquid flow or bioreactor. This chapter first introduces experimental techniques to gauge bioreactor hydrodynamics and then summarizes gas-liquid mass transfer measurement techniques used in bioreactors. [Pg.17]

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