Matrix-enhanced secondary ion mass spectrometry

Wu, K.J. and Odom, R.W., Matrix-enhanced secondary ion mass spectrometry a method of molecular anal3 is of solid surfaces. Anal Chem., 68, 873, 1996. 

Adriaensen, L., Vangaever, E, Lenaerts, J., Gijbels, R. (2005) Matrix-enhanced secondary ion mass spectrometry the influence of MALDI matrices on molecular ion yields of thin organic. Rapid Commun. Mass Spectrom., 19,1017-1024. 

Fitzgerald, J.J.D., Kunnath, E, Walker, A. (2010) Matrix-enhanced secondary ion mass spectrometry (ME SIMS) using room temperature ionic liquid matrices. Anal. Chem., 82,4417, 419. 

The principle of FAB, less frequently referred to as liquid secondary ionization mass spectrometry (LSIMS), is very similar to secondary-ion mass spectrometry (SIMS). However, FAB utilizes a liquid matrix, such as glycerol, in which a sample is dissolved. The matrix is used to enhance sensitivity and ion current stability. 

The ionization methods reported for IMS included MALDI [41,76-80], Secondary Ion Mass Spectrometry (SIMS) [19, 81-86], Matrix-enhanced (ME)-SIMS [87, 88], Desorption Electrospray Ionization (DESI) [89-99], Nanostructure Initiator Mass Spectrometry (NIMS) [100-102], Atmospheric Pressure Infrared MALDI Mass Spectrometry (AP-IR-MALDI-MS) [103], Laser Ablation-inductively Coupled Plasma-Mass Spectrometry (LA-ICP-MS) [104-106], Laser Desorption Postionization (LDPI) [107], Laser Ablation Electrospray Ionization Mass Spectrometry (LAESI) [108, 109], and Surface-assisted Laser Desorption/ioniza-tion Mass Spectrometry (SALDI) [110-112], Another method was called probe electrospray ionization (PESI) that was used for both liquid solution and the direct sampling on wet samples. 

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