Mass Spectrometry in Biological Chemistry Time-of-Flight TOF Instruments

Strategy Calculate the mass of the molecular ion, and identify the functional groups in the molecule. Then write the fragmentation processes you might expect, and compare the masses of the resultant fragments with those peaks present in the spectrum. 

Solution 2-Methyl-3-pentanol, an open-chain alcohol, has M+ = 102 and might be expected to fragment by o- cleavage and by dehydration. These processes would lead to fragment ions of m/z = 84, 73, and 59. Of the three expected fragments, dehydration is not observed (no m/z = 84 peak), but both a clea iges take place (m/z = 73, 59). 

Loss of C3H7 (M+-43) by alpha cleavage gives a peak of mass 59. 

Problem 12.3 1 What are the masses of the charged fragments produced in the following cleavage pathways  

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Mass Spectrometry in Biological Chemistry Time-of-Flight (TOF) Instruments 417... 

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