Mass spectrometer manufacturers hybrid

A laser-induced ToF mass spectrometer (LIMA-2A) was manufactured by Cambridge Mass Spectrometry Ltd., Cambridge, UK, for micro local analysis and was used to analyze thin sections of biological samples in the transmission mode or bulk material in the reflection mode.150,151 Typical LIMA applications in microelectronics include identification of impurities in dielectrics, microlocal analysis, depth profiling, thick film analysis and investigations on hybrid circuits. 

The most common types of MS/MS instruments available to researchers in food chemistry include triple quadrupole mass spectrometers and ion traps. Less common but commercially produced tandem mass spectrometers include magnetic sector instruments, Fourier transform ion cyclotron resonance (FTICR) mass spectrometers, and quadrupole time-of-flight (QTOF) hybrid instruments (Table A.3A.1). Beginning in 2001, TOF-TOF tandem mass spectrometers became available from instrument manufacturers. These instruments have the potential to deliver high-resolution tandem mass spectra with high speed and should be compatible with the chip-based chromatography systems now under development. 

Hybrid linear ion trap-Fourier transform ion cyclotron resonance (FTICR) mass spectrometer, 7T (LTQ-FTICR,Thermo), or equivalent instrument, equipped with an electrospray/nanospray (ESI/ NSI) source and ECD accessory, operated under the control of Xcalibur software package (Thermo Fisher Scientific, San Jose, CA Instrument Configuration, Instrument Setup, Sequence Setup, and Qual Browser modules appropriately created and used) with Bioworks available to preprocess raw data files for database search. ECD may be replaced with ETD and the respective manufacturer s own version of the above software should be used, when alternative instrument is selected. 

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