Manual dexterity

Decline (linear with increasing CoHb level) in maximal oxygen uptake of healthy young men undergoing strenuous exercise decrements in visual perception, manual dexterity, and performance of complex sensorimotor tasks... 

Deerease manual dexterity by adding bulk around fingers (poor fitting, poor grip, stiff)... 

The distribution of the reagent is no longer influenced by the manual dexterity of the operator, the performance of the spray apparatus, the viscosity of the reagent or the drop size of the spray mist. 

Other additional studies or pertinent information which lend support to this MRL Rats exposed to 1,000 ppm trichloroethylene for 3 days showed disturbed sleep cycles (Arito et al. 1993). Rats exposed to 250 ppm for less than 8 hours showed decreased electric shock avoidance and frequency of Skinner box lever press (Kishi et al. 1991). Humans exposed to 27 ppm trichloroethylene for up to 4 hours noted drowsiness, and headache was reported at 81 ppm (Nomiyama and Nomiyama 1977). Humans exposed for 8 hours to 110 ppm showed decreased performance on perception, memory, reaction time, and manual dexterity tests (Salvini et al. 1971). 

Biologic response modifiers (BRMs) are indicated in patients who have failed an adequate trial of DMARD therapy.1 BRMs may be added to DMARD monotherapy (i.e., methotrexate) or replace ineffective DMARD therapy.22 The decision to select a particular agent generally is based on the prescriber s comfort level with monitoring the safety and efficacy of the medications, the frequency and route of administration, the patient s comfort level or manual dexterity to self-administer subcutaneous injections, the cost, and the availability of insurance coverage.23 In general, BRMs should be avoided in patients with serious infections, demyelinating disorders (e.g., multiple sclerosis or optic neuritis) or heart failure.21... 

No neurobehavioral effects were seen in 288 randomly selected males who were occupationally exposed to lead as compared to 181 demographically similar controls (Ryan et al. 1987). The mean PbB level in the exposed workers was 40.1 pg/dL and that of the controls was 7.2 pg/dL. Nineteen tests of neuropsychological performance were conducted. The lead-exposed workers performed no differently from controls on all measures except psychomotor speed and manual dexterity. The authors discounted this difference due to the observation that conflicting results were obtained in two different tests of motor speed and manual dexterity and possible confounding effects of age. There was no evidence that history of previous very high exposure had any effect on performance. 

Caffeine improves psychomotor performance. For example, improvements are seen in manual dexterity (Bernstein et al. 1994). Enhancement of psychomotor performance is most evident when subjects are fatigued (Snyder and Sklar 1984). 

Square formations on top of the r s and/or h s . This person has the abihty to take things apart and put them back together. This writer has good manual dexterity and often good coordination. They are very mechanically minded. 

An epidemiological study found significant increases in neurasthenia (i.e., fatigue, depressed mood, lack of initiative, dizziness, and sleep disturbances) in workers who were chronically exposed to jet fuels by inhalation, oral, and/or dermal exposure (Knave et al. 1978). Also, attention and sensorimotor speed were impaired, but no effects were found on memory function or manual dexterity. EEG results suggest that the exposed workers may have had instability in the thalamocortical system. The limitations of the study are discussed in detail in Section 2.2.1.2 under Respiratory Effects. 

Halothane is used as a clinical anesthetic, and all levels of central nervous system depression can be expected, including amnesia, analgesia, anesthesia, and respiratory depression. Levels ranging from 5000 to 3 0,000 ppm can induce anesthesia, whereas 5000-15,000ppm can maintain it. A 30-minute exposure to 4000 ppm caused amnesia and impairment of manual dexterity, whereas similar exposure to 1000 ppm did not alter the outcome on various psychomotor tests. ... 

One of six volunteers exposed to 150ppm of Stoddard solvent for 15 minutes had transitory eye irritation at 470ppm (2700mg/m ) all subjects had eye irritation and two had slight dizziness. Eight volunteers exposed at 4000 rag/rcL for 50 minutes had some changes in simple reaction time tests but not in perceptual speed, short-term memory, or manual dexterity compared with pre- and postexposure self controls. ... 

Based on effects caused in monkeys and rats, the following are expected in humans 20,000 ppm for 60 minutes, coma and possibly death 10,000 ppm for 30 minutes, marked incoordination 2000ppm for 5 minutes, disturbance of equilibrium. Human subjects exposed to 900-1000ppm for 20 minutes experienced light-headedness, incoordination, and impaired equilibrium transient eye irritation has also been reported at similar concentrations. Impairments in psychomotor task performance such as reaction time, perceptual speed, and manual dexterity have been demonstrated at levels around 350ppm. Other studies at similar exposure levels have failed to show any impairment, but the type of task chosen to test behavioral effects and the times at which behavioral measures were sampled during the course of exposure may explain the variations from study to study." ... 

Psychomotor Impairments were measured by such test batteries as the numerical facility, speed of closure, Purdue pegboard, and Strom-berg manual dexterity tests. Anecdotal reports, both by subjects and by staff, of changes In behavior and mood generally paralleled the other symptoms. The spectrum of the effects and their Intensity is similar to that commonly reported in the recent literature on cannabis studies in other volunteer populations. However, DMHP acetate seemed to elicit more orthostatic hypotension, and cannabis, a greater degree of mental effects. 

The manufacture of pyrotechnics from the Renaissance onward has been conducted, and still is practiced in certain places, as a household art or familiar craft. The artificer1 needs patience and skill and ingenuity for his work. For large-scale factory production, the pyrotechnist has few problems in chemical engineering but many in the control of craftsmanship. His work, like that of the wood-carver or bookbinder, requires manual dexterity but transcends artistry and becomes art by the free play of the imagination for the production of beauty. He knows the kinds of effects, audible and visible, which he can get from his materials. He knows this as the graphic artist knows the appearance of his... 

QUALITATIVE COMMENTS (with 30 mg) Bad taste, worse smell. But I like it. I can paint easily, and wouldn t hesitate to take a little more next time, but this is enough with no one to talk to. Manual dexterity good. Body rather warm. Wouldn t mind fooling around. In retrospect, it has a smooth onset, and is not too stimulating. This is a good one. ... 

The common feature of all the devices described is that they require loading each time they are used, which needs some manual dexterity. In... 

Neurobehavioral examinations are useful for identifying neurotoxicant-mediated deficits, but it is often difficult to localize the site of toxic action from such tests. For example, sensorimotor tests of reaction time, manual dexterity, hand-eye coordination, and finger tapping can indicate either neuromuscular or psychomotor damage. 

A number of studies have been conducted examining the effects of sleep deprivation in medical trainees on performance on a variety of neuropsychological and neurobehavioral tests. Many of these studies have examined the impact of shortterm (on call) sleep loss on psychomotor function, sometimes in combination with simulated medical tasks. Reaction time, vigilance, and manual dexterity are among the parameters that have been shown to be negatively impacted by sleep loss in these studies, although these results are not universally found. For example, sleep deprivation in residents has also been associated with reduced per-... 

To collect equipment blank, place a clean funnel into the sample container. Spray the cleaned surface with analyte-free water from the squeeze bottle and direct the water from the cleaned surface into the funnel. Alternatively, pour the water from the cleaned surface directly into the sample container. (This step requires substantial manual dexterity and may need two persons.)... 

---