Manganese biological chemistry

Yocum, C.F. and Pecoraro, V.C. (1999). Recent advances in understanding the biological chemistry of manganese. Curr. Opin. Chem. Biol., 3, 182-187... 

Christou, G. Manganese carboxylate chemistry and its biological relevance. Acc. Chem. Res. 22... 

Copper and iron complexes with M(/r-0)2M cores were not known before 1994, which is somewhat surprising considering its prevalence with other metal ions, such as manganese. These cores were discovered in copper and iron complexes at nearly the same time and now are touted for their roles in oxidative processes. Their discovery grew out of biological chemistry, but quickly attracted the attention of synthetic chemists. Through the combined efforts of researchers in both disciplines, there are now several examples of complexes with M(/z-0)2M cores having functional oxidative properties. 

E S R.. Fenton. Transferrin Complexes with Non-Physiological and Toxic Metals, David M. Taylor. Transferrins, Edward N. Baker. Galactose Oxidase, Peter Knowles and Nobutoshi Ito. Chemistry of Aqua Ions of Biological Importance, David T. Richens. From a Structural Perspective Structure and Function of Manganese - Containing Biomolecules, David C. Weatherburn, Index. Volume 3,1996,304 pp. 109.50/ 70.00 ISBN 1-55938-642-8... 

BIOINORGANIC CHEMISTRY. Study of the mechanisms involved in the behavior of metal-containing molecules in living organisms, e.g., biological transport of iron, the effect of copper on nucleic acid and iiucleupruleins, molybdenum, and manganese complexes, etc. 

This is the fourth volume of the Specialist Periodical Report covering Transition Metal Chemistry, including the lanthanides and actinides. It is a review of the literature published between October 1973 and September 1974. The layout is similar to that of the earlier reports. Chapter 1 deals with the chemistry of the Early Transition Metals, excluding Scandium, Yttrium, and the Lanthanides. The chemistry of the First Transition Period from Manganese to Copper is given in Chapter 2. The chemistry of the Noble Metals is reported in Chapter 3 and Chapter 5 is concerned with Scandium, Yttrium, the Lanthanides and Actinides. This year we have included an additional Chapter devoted to the chemistry of Zinc, Cadmium, and Mercury, which carries a sub-section concerned with biological aspects of these metals. Again, we have attempted to be comprehensive and have chosen to place much of the data in tabulated form. 

Apart from the catalytic properties of the Mn-porphyrin and Mn-phthalo-cyanine complexes, there is a rich catalytic chemistry of Mn with other ligands. This chemistry is largely bioinspired, and it involves mononuclear as well as bi- or oligonuclear complexes. For instance, in Photosystem II, a nonheme coordinated multinuclear Mn redox center oxidizes water the active center of catalase is a dinuclear manganese complex (75, 76). Models for these biological redox centers include ligands such as 2,2 -bipyridine (BPY), triaza- and tetraazacycloalkanes, and Schiff bases. Many Mn complexes are capable of heterolytically activating peroxides, with oxidations such as Mn(II) -> Mn(IV) or Mn(III) -> Mn(V). This chemistry opens some perspectives for alkene epoxidation. 

Daly KL, DiTullio GR (1996) Particulate dimethylsulfoniopropionate removal and dimethylsulfide production by zooplankton in the Southern Ocean. In Kiene RP, Visscher PT, Keller MD, Kirst GO (eds) Biological and environmental chemistry of DMSP and related sulfonium compounds. Plenum Press, New York, pp 223-238 Davidson AT, Marchant HJ (1987) Binding of manganese by Antarctic Phaeocystis pouchetii and the role of bacteria in its release. Marine Biol 95 481-487 DiTullio GR, Smith WO (1995) Relationship Between Dimethylsulfide And Phytoplankton Pigment Concentrations In The Ross Sea, Antarctica. Deep-Sea Res Part 142 873-892... 

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