Mancozeb mixer-loaders

The purpose of this presentation Is to describe the results of field studies of dermal and Inhalation exposure of applicators and mixer-loaders to the fungicide mancozeb (DITHANE M-45 fungicide, 80Z active Ingredient wettable powder, a product of Rohm and Haas Company, Philadelphia, PA 19105, was used In these studies), a coordination product of zinc Ion and manganese ethyleneblsdlthlo-carbamate, and ethylene thiourea (ETU). The latter compound Is a decomposition product of all EBDC s (mancozeb, maneb, metlram, nabam and zlneb) and also Is produced from EBDC s as an artifact of the analytical procedure for ETU. 

The exposure of mixer-loaders and pilots during the airplane application of mancozeb to potato fields In Michigan, Minnesota and Oregon Is given In Tables VI, Vll and VIII. Mixer-loaders were exposed to mancozeb with forearms being most exposed (1125-9402 yg/body area). Pilots experienced very little exposure, but their hands did range from 58 to 1409 ig/body area. 

Table IX presents the exposure of persons Involved In the ground application of mancozeb by an alrblast sprayer to a tomato field In Ohio. Mixer-loaders again experienced exposure to mancozeb with forearms predominating (2856-3485 iig/body area). Tractor driver—applicators did not experience much exposure, but forearms did range from nondetectable to 1090 yg/body area. Home gardeners using a compressed air sprayer In a homeyard setting experienced little exposure to mancozeb (Table X), except for their ankle and thigh pads (nondetectable-4290 yg/body area).

A number of overall generalizations can be made 1) In all tests protective clothing greatly reduced or eliminated exposure, 2) of the persons examined In these studies mixer-loaders experienced the most exposure, 3) exposure to ETU was generally minimal or not detectable, 4) considerable Individual variation In exposure was evident, and 5) no mancozeb was detected In urine. 

The dermal and inhalation exposure of applicators and mixer-loaders to ethylenebisdlthlocarbamate and ethylenethlourea (ETU) was determined during field applications of mancozeb by airplanes In Michigan, Minnesota and Oregon, by alrblast sprayers In Ohio and by... 

Table VI. Exposure of Mixer-Loaders and Pilots to Mancozeb and ETU During the Application of Mancozeb... 

Brandes, Gordon A. "Applicator, Mixer/Loader Exposure Studies, Mancozeb (Dithane M-45)." Unpublished preliminary report for NCRPIAP Project Nos. 129 (132-NC-MN-F), 130 (133-NC-MI-P), 131 (134-NC-OH-F) and 132 (135-NC-OH-F) by H. L. Blssonette F. Tschirley and H.S. Potter J. Farley and C.C. Powell, respectively, and WRPIAP-Oregon Project by J.M. Witt and F.N. Dost. 1981. 

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