Mammals amine oxidases

The biological function of amine oxidases involves the oxidation of biogenic amines formed during normal biological processes. In mammals, the monoamine oxidases are involved in the control of the serotonin catecholamine ratios in the brain, which in turn influence sleep and EEG patterns, body temperature, and mental depression. Two groups of amine oxidases are involved in the oxidative deamination of naturally occurring amines as well as foreign compounds. 

It is safe to predict that there will be major effort in understanding the biological roles of copper-containing amine oxidases and the relationship to flavin-containing amine oxidases. The diversity of amine oxidases in all forms of life and their involvement in key cellular processes in plants and mammals underline the importance of this objective. 

Plasma amine oxidases are in blood plasma of mammals and include spermine oxidase, which deaminates spermine and other polyamines. 

Amine Oxidase. Copper-containing amine oxidases (CAOs) are ubiquitous metalloenzymes, found in bacteria, yeast, plants, as well as mammals (25). CAO catalyzes the oxidation of primary amines to aldehydes via the reduction of O2 to H2O2. 

On the other hand, bacteria, yeast, plants, and mammals all possess copper-containing proteins, called copper amine oxidases or CAOs, which serve to... 

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