Maltitol solution

Maltitol solutions Maltitol syrups Malto-dextrin... 

Hydrogenated starch hydrolysates (HSH) is a term used to describe a range of products which do not contain sorbitol or maltitol as a primary component, ie, at least 50%. HSH symps contain a distribution of sorbitol, maltitol, and other hydrogenated oligo and polysaccharides. Symps containing maltitol at a level of at least 50% are referred to as Maltitol symps or Maltitol solutions. 

Maltitol, lactitol, isomalt, maltitol solutions (symps), and hydrogenated starch hydrolysates (HSH) have GRAS petitions filed with the FDA and are being sold commercially under self-determined GRAS status. Maltitol, owing to its lower negative heat of solution, is often preferred over mannitol as the... 

Compressible sugar Confectioner s sugar Dextrose Glycerin Lactose Liquid glucose Maltitol solution Mannitol Sorbitol Sucrose Xylitol Intense... 

BP Liquid maltitol PhEur Maltitolum liquidum USPNF Maltitol solution... 

The USPNF 23 describes maltitol solution as an aqueous solution of a hydrogenated, partially hydrolyzed starch. It contains, on the anhydrous basis, not less than 50% w/w of D-maltitol (C12H24O11) and not more than 8.0% w/w of D-sorbitol (CgHi406). See also Section 18. 

Maltitol solution is used in oral pharmaceutical formulations as a bulk sweetening agent, either alone or in combination with other excipients, such as sorbitol. Maltitol solution is also used as a suspending agent in oral suspensions as an alternative to sucrose syrup since it is viscous, noncariogenic, and has a low calorific value. It is also noncrystallizing and therefore prevents cap-locking in syrups and elixirs. 

Maltitol solution is additionally used in the preparation of pharmaceutical lozenges and is also used in confectionery and food products. 

Maltitol solution is a colorless and odorless, clear viscous liquid. It is sweet-tasting (approximately 75% the sweetness of sucrose). 

Osmolarity the osmolarity of an aqueous maltitol solution is similar to that of a sucrose solution of the same concentration. A 10% v/v aqueous solution of Lycasin 80/55 (Roquette) is iso-osmotic with serum. 

Viscosity (dynamic) maltitol solution is a viscous, syrupy, liquid. At 20°C, a solution of Lycasin 80/55 (Roquette) containing 75% of dry substances has a viscosity of approximately 2000 mPas (2000 cP). With increasing temperature, the viscosity of a maltitol solution is reduced see Figure 1. The viscosity of maltitol solutions also decreases with decreasing concentration of dry solids, at a constant temperature. Maltitol solution may also be mixed with sorbitol solution to obtain blends of a desired viscosity. 

Figure 1 Viscosity of maltitol solution [Lycasin 80/55), containing 75% of dry substances, at different temperatures.

Formulations containing maltitol solution should be preserved with an antimicrobial preservative such as sodium benzoate or a mixture of parabens. Maltitol solution is noncrystallizing. 

Maltitol solution should be stored in a well-closed container, in a cool, dry place. 

Maltitol solution is prepared by the hydrogenation of a high-maltose syrup that is obtained from starch by enzymatic hydrolysis. The maltitol solution produced from this process consists of the hydrogenated homologs of the oligosaccharides contained in the original syrup. 

Maltitol solution is used in oral pharmaceutical formulations, confectionery, and food products and is considered to be less cariogenic than sucrose. It is generally regarded as a nontoxic, nonallergenic, and nonirritant material. However, excessive oral consumption (more than 50 g daily) may cause flatulence and diarrhea. 

The WHO, in considering the safety of maltitol solution, did not set a value for the acceptable daily intake since the levels used in food to achieve a desired effect were not considered a hazard to health. 

Maltitol solution mannitol sorbitol solution 70% xylitol. 

E504 Magnesium Carbonate Anhydrous 424 E965 Maltitol Solution 440... 

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