Malarial parasite Plasmodium berghei

Nagarajan, K. (1964). Pyruvate and lactate levelsin relationship to the nicotinamide adenine dinucleotide levels in malarial parasites Plasmodium berghei). Biochim. Biophys. Acta 93, 176-179. 

A marine diatom (Sullivan and Volcani 1974) and the malarial parasite Plasmodium berghei (Seed et al. 1974) were found to contain membrane-bound sialic acid. Studies in the authors laboratory have confirmed the presence of Neu5Ac and Neu5Gc in a ratio of 9 1 in Trypanosoma cruzi. 

The immune system of the mouse may also be susceptible to the effects of acute oral exposures to di-/ -octylphthalate (Dogra et al. 1989). Three-month-old Swiss albino mice were exposed to di-n-octylphthalate by gavage for 5 days at 0, 650, or 2,600 mg/kg/day (acute LD50 was 13,000 mg/kg). Mice were subsequently exposed by intraperitoneal injection to either encephalomyocarditis virus or the malarial protozoan, Plasmodium berghei. Maximum mortality levels were reached 8-10 days after viral infection and were 20% (0 mg/kg/day), 40% (650 mg/kg/day), and 70% (2,600 mg/kg/day). Malarial lethality reached plateau levels 4-11 days postinfection of approximately 20% (0 mg/kg/day), 25% (650 mg/kg/day), and 70% (2,600 mg/kg/day), then increased to 55%, 70%, and 85%, respectively, by postinfection day 19. Respective mean survival times were calculated to be 13.50, 12.15, and 6.25 days. During the first 14 days after protozoal infection, the percentage of mouse erythrocytes infected with the parasite in the high-dose... 

Phisphumvidhi, P., and Langer, B. W., Jr. (1969). Malarial parasite metabolism The lactic acid dehydrogenase of Plasmodium berghei. Exp. Parasitol. 24, 37-41. 

Plasmodium species. Much of the information on purine metabolism in malaria parasites has been obtained by comparing the salvage abilities of uninfected erythrocytes to infected erythrocytes. Although current emphasis is on the human malarial parasite, P. falciparum, much of the information on purine metabolism was obtained using intraerythrocytic forms of rodent (P. berghei) (52) and avian (P. lophurae) (53) parasites. Since no major differences seem to exist between these species and P. falciparum, the latter will be used as the representative species. 

P. berghei isolated from mouse red blood cells also contains a cyanide-sensitive SOD activity. Plasmodial and mouse enzymes are indistinguishable electrophoretically. These results suggest that the malarial cyanide-sensitive SOD may be entirely of host origin and stored by the parasite. Accordingly, plasmodium isolated from mouse red blood cells contain mouse cyanide-sensitive SOD, whereas rat-derived parasites contain the rat enzyme (78). Another, peroxide-sensitive, apparently manganese-containing SOD, has been described in P. falciparum (79). Two Babesia species (B. hylomysci and... 

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