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Malaria herbal medicine

Herbal medicines that control the attack of diseases such as asthma and malaria should be taken 1-2 hours before an attack. [Pg.17]

Xu, Y. J. Capistrano, R. s. Dhooghe, L. Foubert, K. Lemiere, F. Maregesi, S. Balde, A. Apers, S. Pieters, L., Herbal medicines and infectious diseases Characterization by LC-SPE-NMR of some medicinal plant extracts used against malaria, PlantaMed., 2011, Feb 15 [Epub ahead of print]. [Pg.212]

Chinese herbal medicine may have made a contribution to the treatment of malaria. The herb Quinghao (Artemisia annua), in use over a millennium, has finally yielded its active principle quinghaosu or artemisinine (Fig. 7-6), a sesquiterpene lactone containing a peroxide bridge. Clinical evaluation of it and several derivatives in the late 1970s was reported to have achieved successful treatment in over 2,000 patients, many with chloroquine-resis-tant falciparum. Their activity is blood schizonticidal. The mechanism does not appear to be antifolate or intercalation. The peroxide is essential, which raises a suspicion of free radical damage to the parasite. [Pg.290]

However, the most modern drugs in our armoury to fight malaria infections are derivatives of artemisinin. This natural product originates from the sweet wormwood, Artemisia annua), a traditional Chinese herbal medicine, which had already been in use for malaria treatment some 1,300 years prior to quinine, albeit its active principle was only discovered in the 1970s. [Pg.455]

To use a more sophisticated example, we can look to the products of the neem tree (Azadirzchta indica), a tropical plant that is known for its pesticidal properties. The seed of this tree is abundant with limonoids and simple terpenoids that are responsible for its biological activity. One particular limonoid found in the seed is Azadirachtin (2.134). The bioactivity of Azadirachtin potentially leads to a wide range of applications in herbal medicine and healthcare products for the treatment of malaria and tuberculosis and in anti-worm, clotting, and blood-detoxification preparations. These uses of Azadirachtin as a biopesticide or herbal medicine is limited due to solubility constraints in water and its instability as a result of its propensity to undergo complicated, irreversible rearrangements under acidic, basic and photolytic conditions. Consequently, there has been much research in the structural modification of Azadirachtin to overcome its solubility constraints to increase stability. This process normally involves many protection and deprotection synthetic steps and chromatographic separations. [Pg.93]


See other pages where Malaria herbal medicine is mentioned: [Pg.263]    [Pg.1131]    [Pg.279]    [Pg.218]    [Pg.553]    [Pg.267]    [Pg.2]    [Pg.173]    [Pg.571]    [Pg.134]    [Pg.74]    [Pg.186]    [Pg.59]    [Pg.136]    [Pg.227]    [Pg.3]    [Pg.21]    [Pg.1035]    [Pg.1038]    [Pg.405]    [Pg.158]   
See also in sourсe #XX -- [ Pg.42 , Pg.44 ]




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