Malaria clinical presentation

The clinical presentation of malaria can be quite variable. Normally, the appearance of a prodrome with headache, abdominal pain, fatigue, fever, and chills, which coincides... 

Malaria is caused by a one-celled parasite from the genus Plasmodium. Four species of Plasmodium infect humans, each appearing somewhat different under the microscope and producing somewhat different clinical presentations. Two or more species can live in the same area and can infect a single individual at the same time (National Institute of Allergy and Infectious Diseases, 2002). The four species are as follows ... 

TABLE 113—1. Clinical Presentation of Malaria Initial Presentation... 

Prevalence and clinical presentation of glucose-6-phosphate dehydrogenase deficiency in Pakistani Pathan and Afghan refugee communities in Pakistan implications for the use of primaquine in regional malaria control programmes. 

MGN may be primary or secondary to other conditions (e.g., hepatitis B, malaria, congenital syphilis, SEE, drugs, and neoplasms). The latter cases predominate in children (Cameron 1990). Clinical presentation is with NS and microhaematuria... 

A population pharmacokinetic study of intramuscular quinine (loading dose 20 mg/kg salt diluted 1 1 in water) in 120 Ghanaian children with severe malaria showed predictable profiles, which were within the target range for quinine (15-20 pg/ml) and independent of clinical and laboratory variables (1). Adverse events included skin induration or abscesses at the injection site (12%), all of which resolved without surgical intervention, and hypoglycemia (10%), a special risk in children who were hypoglycemic at presentation. 

Diep, R. R, Lien, L., and Hofman, J., A criteria-based clinical audit on the case-management of children presenting with malaria at Mangochi District Hospital, Malawi, World Hosp Health Serv 43(2) 21-29,2007. 

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