Major depressive disorders guidelines

Practice guideline for the treatment of patients with major depressive disorder (revision). Am J Psychiatry 2000 157(4 suppl) lM5. 

Bauer M et al. (2002). World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of unipolar depressive disorders. Part 1 Acute and continuation treatment of major depressive disorder. World Journal of Biological Psychiatry, 3, 5-43. 

American Psychiatric Association. Practice guidelines for major depressive disorder (MDD) in adults. Am J Psychiat 2000 157(Suppl 4) 1 5. 

Note Doses are provided as general guidelines only, and are not meant to be definitive. All doses must be individualized and monitored through appropriate clinical and/or laboratory means. ADHD, attention-deficit hyperactivity disorder bid, twice daily c, capsule CYP, cytochrome P450 EKG electrocardiogram FDA, Food and Drug Administration IM, intramuscular MDD, major depressive disorder OCD, obsessive-compulsive disorder PDD, pervasive developmental disorder qd, once daily qhs each bedtime qoWk, every other week t, tablet tid, three times daily TS, Tourette s syndrome WBC, white blood cell count. 

American Psychiatric Association Practice Guideline for the Treatment of Patients With Major Depressive Disorder, 2nd Edition. Washington, DC, American Psychiatric Association, 2000... 

Our approach to both acute and maintenance therapy is consistent with the American Psychiatric Association guidelines for the treatment of major depressive disorder in adults (292). 

Practice Guidelines for Major Depressive Disorder in Adults... 

ADHD, attention-deficit hyperactivity disorder EKG, electrocardiogram GI, gastrointestinal MD, major depression MR, mental retardation OCD, obsessive-compulsive disorder PTSD, post-traumatic stress disorder. Trade names are in parentheses. Doses are general guidelines. All doses must be individualized with appropriate monitoring. Weight-corrected doses are less appropriate for obese children. 

It is still debated whether patients with two previous episodes should receive maintenance treatment. Overall, maintenance treatment has been recommended for adult depressed patients with two episodes who have one or more of the following criteria (Depression Guideline Panel, 1993) (1) a family history of bipolar disorder or recurrent depression, (2) early onset of the first depressive episode (before age 20), and (3) both episodes were severe or life threatening and occurred during the past 3 years. Given that depression in youth has similar clinical presentation, sequelae, and natural course as in adults, these guidelines should probably be applied for youth with two previous major depressive episodes. 

Treatment Guidelines for Schizophrenia, Major Depression, Bipolar Illness, Panic Disorder, Generalized Anxiety Disorder, Obsessive Compulsive Disorder and Social Anxiety Disorder, American Pharmaceutical Association Publications Bethesda, Maryland, copyright 1998-2000. 

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