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Magnolol

Of the many types of phenolic compounds, not many have been shown to possess AChE inhibitory activity. The root and stem bark of Magnolia officinalis Rehd. Et Wils. contains the biphenolic lignans, honokiol (72) and magnolol (73). Both lignans increased ChAT activity and inhibited AChE activity in vitro, and increased hippocampal ACh release in vivo) These two compounds also appeared to have antioxidant antiinflammatory... [Pg.408]

Hou YC, Chao PD, Chen SY, Honokiol and magnolol increased hippocampal acetylcholine release in freely-moving rats, Am J Chin Med 28 379—384, 2000. [Pg.425]

Lo YC, Teng CM, Chen CF, Magnolol and honokiol from Magnolia officinalis protect tat heatt mitochondria against lipid petoxidation, Biochem Pharmacol... [Pg.425]

Disodium-2,2 -dithio-bis-ethane sulfonate (BNP7787) intracellular conversion products honokiol and magnolol in fresh Magnolia obovata ... [Pg.91]

Baicahn and baicalein in rat plasma honokiol and magnolol in branches and leaves of Magnolia obovata quercetin in human plasma ... [Pg.91]

Kotani, A., Kojima, S., Hakamata, H., Jin, D., and Kusu, R, Determination of honokiol and magnolol by micro HPLC with electrochemical detection and its application to the distribution analysis in branches and leaves of Magnolia obovata. Chemical and Pharmaceutical Bulletin (Tokyo) 53(3), 319-322, 2005. [Pg.100]

Magnolol Mairin Makisterones Makulor Malic acid... [Pg.450]

Extracts of a mixture of honiokol 202 and magnolol 203 (the main constituents of the stem bark of Magnolia abovata thumb and Magnolia officinalis rhed, used in traditional Chinese medicine) have been separated by acid-catalyzed transformation of magnolol with dimethoxypropane into 204 (Scheme 57) <2006JME3426>. [Pg.352]

Xu, Q., Yi, L. T., Pan, Y., Wang, X., Li, Y. C., et al. (2008) Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents. Prog Neuropsychopharmacol Biol Psychiatry 32, 715-725. [Pg.281]

Magnolol (lignan) Magnolia obovate, M. officinalis (Magnoliaceae) MMP-9 (-0.1 pM) [95]... [Pg.582]

Simple lignans involving a Phe-C -C -Phe structure are illustrated by the antioxidant and Ca2+ channel blocker nordihydroguaiaretic acid (NDGA) (3,4-dihydroxyphenyl-CH2-CH(CH3)-CH(CH3)-CH2-(3, 4 -dihydroxyphenyl)), the bitter-tasting phyllanthin and the cAMP phosphodiesterase inhibitor ar-hinokiresinol. Simple lignans of the C3—Phe—Phe—C3 kind are illustrated by the antibacterials honokiol and the protein kinase inhibitor magnolol. [Pg.24]

Magnolol product diversity within any one genus) Sassafras randaiense (Lauraceae) GABAA-R APL (6) [anti-... [Pg.106]

Magnolol Sassafras randaieme (Lauraceae) PKC [blocks PE binding site]... [Pg.314]

Magnolol Sassafras randaiense (Lauraceae) [root], 1 ipHSDH (type 2)... [Pg.460]

Other uses of ferric chloride as an oxidant are for conversion of the dithiol (8) to ( )-thioctic acid (9) and of chavicol (10) to magnolol (11)J... [Pg.929]

Magnolol is a bioactivator extracted from Magnolia officinalis with protective effects on cholinergic neurons. Magnolol restores the impaired abilities of learning and memory induced by scopolamine, and AChE, NOS, and SOD activities in mice [277]. [Pg.414]

Li YS, Hong YF, He J, Lin JX, Shan YL, Fu DY et al (2013) Effects of magnolol on impairment of learning and memory abilities induced by scopolamine in mice. Biol Pharm Bull 36 764-771... [Pg.532]

Dean JR, Liu B, Price R. Extraction of magnolol from Magnolia officinalis using supercritical fluid extraction and phytosol solvent extraction. Ph5dochem Anal 1998 9 248-252. [Pg.569]

Miao HJ, Liu ZL, Li YH. Analysis of magnolol and honokiol in Magnolia officinalis Rehd et Wils by supercritical fluid extraction and capillary gas chromatography. Yaowu Fenxi Zazhi 1998 18 182-185. [Pg.569]

See other pages where Magnolol is mentioned: [Pg.77]    [Pg.11]    [Pg.11]    [Pg.12]    [Pg.16]    [Pg.22]    [Pg.224]    [Pg.224]    [Pg.362]    [Pg.108]    [Pg.543]    [Pg.266]    [Pg.116]    [Pg.853]    [Pg.853]    [Pg.50]    [Pg.387]    [Pg.549]    [Pg.589]    [Pg.589]    [Pg.590]   
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