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Magnetic targeting

Magnetic targeting is used when a therapy has limited ability to be chemically targeted to specific types of cells or tissues due to high nonspecific binding. The force felt by a magnetic moment of value in in a gradient field is... [Pg.466]

The magnetic targeting force must compete with the force due to linear blood-flow rates of about 0.05 cm/s in capillaries to 10 cm/s in arteries and 50 cm/s in the aorta. Iron-oxide nanoparticles require flux densities at the target site on the order of 0.1 to 1.0 T with field gradients ranging from 8 T/m (femoral arteries) to over 100 T/m for carotid arteries [39, 64]. [Pg.466]

Pengcheng D., Tingmei W., and Peng L. Double-walled hollow polymeric microspheres with independent pH and temperature dual-responsive and magnetic-targeting function from onion-shaped coreshell structures. Colloids Surf. B 102 (2013) 1-8. [Pg.1109]

Dutta R. K., Sahu S. (2012b). Development of a novel probe sonication assisted enhanced loading of 5-FU in SPION encapsulated pectin nanocarriers for magnetic targeted drug delivery system. Eun l PhanrhBio hai 82, 58-65. [Pg.467]

Rudge S, Peterson C, Vessely C, Koda J, Stevens S, Cat-terall L (2001) Adsorption and desorption of chemotherapeutic drugs from a magnetically targeted carrier (MTC). J Control Release 74 335-340... [Pg.155]

Goodwin, S.C., Bittner, C.A., Peterson, C.L., Wong, G., 2000. Single Dose Toxicity Study of Hepatic Intra-Arterial Infusion of Doxorubicin Coupled to a Novel Magnetically Targeted Drug Carrier. University of Los Angeles Medical School. [Pg.29]

Studies showed that particles as large as 1-2 pm could be concentrated at the site of intracerebral rat glioma-2 (RG-2) tumors a later study demonstrated that 10-20 nm magnetic particles were even more effective in targeting these tumors in rats. Studies of magnetic targeting in humans demonstrated that the infusion of ferrofluids was well tolerated in most patients, and the ferrofluid could be... [Pg.193]

FIGURE 1 The classical scheme of magnetically targeted nanosystem for a smart delivery of therapeutic products. [Pg.316]

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See also in sourсe #XX -- [ Pg.461 , Pg.466 , Pg.467 , Pg.473 , Pg.474 , Pg.475 , Pg.480 ]

See also in sourсe #XX -- [ Pg.8 ]



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Targeted using magnetic resonance

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