Magnetic Resonance Imaging MRI contrast agents

In particular for fullerenes, antioxidant properties and photodynamic activity are presented in detail, together with the analysis of gadolinium endohedrals as magnetic resonance imaging (MRI) contrast agents. Moreover, drag delivery based on carbon nanomaterials has been illustrated. 

In another case, PAs were designed to function as magnetic resonance imaging (MRI) contrast agents (Bull et al. 2005) by covalently linking the peptide portion to a derivative of l,4,7,10-tetraazacyclododecane-l,4,7,10-tetraacetic acid followed by chelation of Gd ions by this moiety. The PAs were modified such that self-assembly produce either nanofibers or spherical micelles. The application of this self-assembling system could be extended to noninvasive MRI of PA scaffolds in vivo. 

The major emphasis of the research carried out to date in the expanded porphyrin area has been concerned with the synthesis and characterization of new systems. However, significant effort has been devoted recently to exploring the use of these macrocycles as sensitizers for photodynamic therapy (PDT) and as magnetic resonance imaging (MRI) contrast agents. These two applications serve as the most visible of several potential areas where expanded porphyrins could provide an improvement over existing technology. In this section, therefore, we review the work to date relative to both PDT and MRI and also comment briefly about the other areas of potential utility. 

Clinical Magnetic Resonance Imaging (MRI) Contrast Agents... 

Contrast agents can also be used to enhance computed tomography (CT) scans and magnetic resonance imaging (MRI). Contrast agent use with CT scans is particularly... 

The porosity of the particles could be shown by encapsulating an aqueous solution of a gadolinium-based magnetic resonance imaging (MRI) contrast agent [Gd-diethylenetriamine penta acetic acid (DTPA)]. As the Gd complex is still accessible by water from the capsule exterior, changing the water s proton relaxation time, it can be concluded, that the shell is porous and allows water to diffuse into the capsules, but restricts the complex to the interior [78]. 

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