Magic angle spinning , solid-state

High-Resolution Magic Angle Spinning and Cross-Polarization Magic Angle Spinning Solid-State NMR Spectroscopy... 

In this review we shall emphasize some of the unique features of HREM and, in so doing, illustrate how, in association with one or other of the additional techniques mentioned above, or in association with separate studies (e.g. magic-angle-spinning solid-state NMR), HREM has clarified several new, or hitherto enigmatic, features of the chemistry of inorganic solids. In particular we discuss, how ... 

R. Verel. Adiabatic methods for Homonuclear Dipolar Recoupling in Magic Angle Spinning Solid-State NMR. PhD thesis, ETH Zurich, Diss. Nr. 14152, 2001. 

Abstract Membrane proteins represent an important and challenging frontier in structural biology they mediate fundamental and medically important processes but are challenging targets for structure/ function studies. Magic angle spinning solid-state NMR methods for structure determination of proteins have developed rapidly in... 

The mechanism of the accelerated sulfur vulcanisation of EPDM is probably similar to that of the highly unsaturated polydiene rubbers. The vulcanisation of EPDM has been studied with emphasis on the cure behaviour and mechanical and elastic properties of the crosslinked EPDM. Hardly any spectroscopic studies on the crosslinking chemistry of EPDM have been published, not only because of the problems discussed in Section 6.1.3 but also because of the low amount of unsaturation of EPDM relative to the sensitivity of the analytical techniques. For instance, high-temperature magic-angle spinning solid-state 13C NMR spectroscopy of crosslinked EPDM just allows the identification of the rubber type, but spectroscopic evidence for the presence of crosslinks is not found [72]. 

M. H. Levitt, Symmetry-based pulse sequences in magic-angle spinning solid-state NMR. in Encyclopedia of Nuclear Magnetic Resonance, D. M. Grant and R. K. Harris (eds.), Supplementary Volume, Wiley, Chichester, 2002, pp. 165-196. 

Solid-state NMR also can be applied to membrane proteins in lipid bilayers, and recent advancements in magic angle spinning solid-state NMR show promise for stmcture determination. Although the stmctures of small crystalline proteins (89) and membrane bound peptides (90) have been determined, the stmcture of a polytopic membrane protein has yet to be reported. The major necessity that is required to push the technique forward is the de novo sequential chemical shift assignment of the amino acid residues, and in the last few years, several groups have reported successful strategies (91, 92). 

Keywords Magic-angle spinning Solid state Nuclear magnetic resonance... 

R. Verel, M. Baldus, M. Nijman, J. W. M. van Os and B. H. Meier, Adiabatic homonuclear polarization transfer in magic-angle-spinning solid-state NMR. Chem. Phys. Lett., 1997, 280. 31-39. 

FIGURE 2. The cross-polarization, magic-angle-spinning, solid state C NMR spectrum of stream humic acid from the Ogeechee River near Louisville, Georgia during December 1981. 

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