Macular degeneration diagnosis

Clinical presentation involves a normal postoperative course for several weeks to 6 months, followed by vision loss that is often the only symptom but may be accompanied by photophobia, injection, anterior chamber reaction, or Amsler grid distortion. There is some evidence of an increased prevalence of early age-related macular degeneration in eyes that have imdergone cataract surgery. Also, diabetic retinopathy and clinically significant diabetic macular edema may both be exacerbated by CE. Therefore the differential diagnosis of postoperative vision loss must include these conditions. 

Castillo, M., et al. Optical coherence tomography for the diagnosis of neovascular age-related macular degeneration a systematic review. Eye 28(12), 1399-1406 (2014)... 

Cardiovascular A 64-year-old woman treated for macular degeneration with intraocular injections of bevacizumab presented with chest pain, nausea and vomiting. After an initial diagnosis of acute coronary syndrome and anticoagulation treatment with intravenous heparin, she remained stable without chest pain or shortness of breath and with no evidence of arrhythmias. This may be the first report of an association between intraocular bevacizumab and reversible myocardial dysfunction with a pattern similar to stress-induced cardiomyopathy (also called Takotsubo cardiomyopathy or apical ballooning), although clear evidence for a causal relationship is lacking [97 ]. 

Biological Applications Zinc indicator " early diagnosis of prostate cancer treating age-related macular degeneration (AMD), amyloidosis disorders, autoimmune diseases, herpes virus infection ... 

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