Macrophages epithelial surface

One approach to examining inflammation is the assay reported by Elgebaly et al. (1987) for the release of chemotactic factors. Earlier work has elegantly shown that neutrophil or macrophage infiltration from either the endothelial or epithelial surface... 

S. Worgall, P. L. Leopold, G. Wolff, B. Ferris, N. VanRoijen, and R. G. Crystal, Role of alveolar macrophages in rapid elimination of adenovirus vectors administered to the epithelial surface of the respiratory tract, Hum. Gene Ther. 8 1675 (1997). 

Dieu-Nosjean, M.C. et al. (2000) Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors. The Journal of Experimental Medicine, 192, 705-718. 

Despite the fact that most of the alveolar surface is composited of alveolar epithelium, three primary types of cells are present in the alveoli type I alveolar cells, type II alveolar cells, and alveolar macrophages. Type I alveolar cells are also referred to as squamous pulmonary epithelial cells and are the continuous lining of the alveolar sac. Type II alveolar cells are also referred to as septal cells. Type II alveolar cells secrete the alveolar fluid that is necessary to keep the surface moist and to maintain surface tension of the alveolar fluid surface tension is necessary to keep the alveoli from collapsing. Alveolar fluid is a suitable environment for proteins when compared to the low pH and high protease levels associated with the intestine... 

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