Macrophage-dendritic cell interaction

Dendritic Cells 1 2. Macrophage-Dendritic Cell Interactions 8... 

Macrophage dendritic cell interaction in the regulation of the IgE response in asthma. Clinical and Experimental Allergy, 23, 4-6. 

The class II proteins are produced mainly within specific cells, known as antigen-presenting cells (APC). Their role is to prepare antigens derived from the pathogens in such a way that they can interact with the T-helper cell receptor. Since this is their only role, they are sometimes called professional antigen-presenting cells , i.e. other immune cells can also present peptides to T-helper cells (e.g. macrophages, B-lymphocytes) but this is not their prime role. The professional APCs are also known as dendritic cells. 

Shared receptors are defined as able to bind more than one CK this concept is only valid inside each CK family. For example CCL20, alternatively named liver and activation-regulated CK (LARC), macrophage inflammatory protein-da (MIP-3a) or Exodus-1, is the only CK known to interact with CC CK receptor 6 (CCR6), a property shared with the antimicrobial (i-defensins. The ligand-receptor pair CCL20-CCR6 is responsible for the chemoattraction of immature dendritic cells, effector/memory T cells, and B cells and plays a role at skin and mucosal surfaces under homeostatic and... 

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