Macrocyclic Quinoxaline Compounds as Anticancer Drugs and Inhibitors of Hepatitis Virus

3 Macrocyclic Quinoxaline Compounds as Anticancer Drugs and Inhibitors of Hepatitis C Virus 

There are three types of the quinoxaline macrocyclic compounds known with important pharmacological properties. They differ in whether the quinoxaline fragment enters the stmcture of the macrocyclic system and if it does, then what follows. 

The macrocycle 208 is the inhibitor of the cylin-dependent kinase (Cdks) (Hirai etal. 2011). 

The Zhan 1 catalysts are the commercially available mthenium catalyst for RCM processes. 

Compounds 224, 232, 233 are transformed into water-soluble derivatives 218-220 possessing antiviral properties, as inhibitors of HCV. 

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