Lysergic acid diethylamide abuse

Schedule I Substances with no accepted medicinal use in the United States and a high potential for abuse for example, heroin, marijuana, lysergic acid diethylamide (LSD), mescaline, and psilocybin. 

Lysergic acid diethylamide Central nervous system (CNS) 5-HT2and dopamine agonist 5-HT2 antagonist in periphery Hallucinations psychotomimetic None widely abused Oral duration several hours Toxicity Prolonged psychotic state, flashbacks... 

The National Household Survey on Drug Abuse (NHSDA), which is conducted by the Substance Abuse and Mental Health Services Administration (SAMH-SA), provides statistical data on illegal drug use in the United States. For the purpose of the survey, hallucinogenic drugs were defined to include lysergic acid diethylamide (LSD), phencyclidine (PCP), psilocybin, peyote, and ecstasy. 

B. Widdop. Screening for Drugs of Abuse (II) Cannabinoids, Lysergic Acid Diethylamide, Buprenorphine, Methadone, Barbiturates, Benzodiazepines and Other Drugs. Annals of Clinical Biochemistry 34 (5) (1997) 460-510 Shannon, M. Toxicology Reviews Physostigmine. Pediatric Emergency Care 14 (3) (1998) 224-226. 

Lysergic acid diethylamide (LSD) is an illicit drug abused as a hallucinogen. 

Morning glory seeds contain the toxin lysergic acid hydroxyethylamide, which has one-tenth the potency of lysergic acid diethylamide (LSD). The toxic effect, at an equivalent dose, is similar to that of LSD. To avoid abuse of morning glory seeds, commercial seed producers treat the seeds with essential oils, which are irritants, which induce nausea, vomiting, and abdominal pain which precede the psychedelic effects. 

The paucity of literature on solvent abuse compared with other drug abuse contrasts with its prevalence and medical importance. In New York State, adolescent solvent abuse approximated that of lysergic acid diethylamide (LSD) (Stephens et al. 1978). Solvent abuse parallels marijuana use until the eighth grade, when solvent use declines and marijuana use increases (Beauvais 1992). Solvent use appears on the rise, reflected by a 1991 study that found greater use of solvents than cocaine by adolescents (Beauvais 1992). One study in the United States found that 11.2% of high school students... 

The Department of Health, Education, and Welfare s Bureau of Drug Abuse Control was responsible for the control of dangerous drugs, including depressants, stimulants, and hallucinogens, such as lysergic acid diethylamide (LSD). 

Drug abuse has become a major problem for the United States and many other countries around the world. The analysis of drugs of abuse now accounts for a major proportion of the workload of state and local forensic science laboratories. The most commonly encountered drugs of abuse at the present time are cannabis (marijuana), cocaine (crack), heroin, phencyclidine (PCP), lysergic acid diethylamide (LSD), amphetamines, including 3,4-methylenedioxyamphetamine (MDA) and 3,4-methylenedioxymethamphetamine (MDMA), and other designer drugs. 

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