Lymphomas extranodal marginal zone lymphoma

Flaviviridae the hepacivirus family is represented by its single member the hepatitis C virus. This important human hepatitis virus is reported to be associated with hepatocellular carcinoma, lymphoplasmacytic lymphoma, extranodal marginal zone B-cell lymphoma and monoclonal lymphoid proliferation. 

Table 2 Differential Diagnosis of Nodular Lymphoid Hyperplasia (NLH), Lymphocytic Interstitial Pneumonia (LIP), Follicular Bronchiolitis (FB), and Extranodal Marginal Zone Lymphoma (Maltoma)... 

Extranodal marginal zone B-cell lymphoma of MALT type... 

N. L., CD5+ extranodal marginal zone B-cell (MALT) lymphoma. A low grade neoplasm witii a propensity for bone marrow involvement and relapse. Am. J. Clin. Pathol. 105, 31—37 (1996). 

Isaacson, P. G., Muller-Hermelink, H. K., Piris, M. A., Berger, F., Nathwani, B., Swerdlow, S. H., and Harris, N. L., Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). In World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues (E. S. Jaffe, N. L. Harris, H. Stein, and J. W. Vardiman, eds.), pp. 157-160. IARC Press, Lyon, 2001. 

R9. Remstein, E. D., James, C. D., and Kurtin, P. J., Incidence and subtype specificity of API2-MALT1 fusion translocations in extranodal, nodal, and splenic marginal zone lymphomas. Am. J. Pathol. 156,1183-1188 (2000). 

EXTRANODAL MARGINAL ZONE B-CELL LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT) TYPE... 

Lymphoproliferative malignancies occur in approximately 7% of patients with primary SjS, a prevalence that is 40 times higher than in the general population (192). MALT-type lymphomas of the lung (Fig. 9), also called BALT lymphomas, are extranodal marginal-zone B-cell neoplasms, not usually associated with viruses (192). BALT lymphoma is usually detected in routine or incidental examination. HRCT features are similar to those of patients without SjS (214). The course of the disease is quite indolent, even in cases with extensive or prominent HRCT abnormalities (214). 

B6. Bertoni, R, Conconi, A., Lutrdnari, S., Realini, C., Roggero, E., Baldini, L., Carobbio, S., Cavalli, R, Neri, A., and Zucca, E., Lack of CD95/FAS gene somatic mutations in extranodal, nodal and splenic marginal zone B cell lymphomas. Leukemia 14, 446-448 (2000). 

R13. Royer, B., Cazals-Hatem, D., Sibilia, J., Agbalika, F., Cayuela, J. M., Soussi, T., Maloisel, F., Clauvel, J. P., Brouet, J. C., and Mariette, X., Lymphomas in patients with Sjogren s syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses. Blood 90, 766-775 (1997). 

Y9. Yonezumi, M., Suzuki, R., Suzuki, H., Yoshino, T., Oshima, K., Hosokawa, Y., Asaka, M., Morishima, Y., Nakamura, S., and Seto, M., Detection of AP12-MALT1 chimaeric gene in extranodal and nodal marginal zone B-cell lymphoma by reverse transcription polymerase chain reaction (PCR) and genomic long and accurate PCR analyses. Br. J. Haematol. 115, 588-594 (2001). 

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