Luteinizing hormone regulation

SERM, selective estrogen receptor modulator SERD, selective estrogen receptor down regulator LHRH, luteinizing hormone-releasing hormone. 

Sabharwal, P, Varma, S., and Malarkey, W.B., Human thymocytes secrete luteinizing hormone An autocrine regulator of T-cell proliferation, Biochem. Biophys. Res. Com., 187, 1187, 1992. 

Anterior part produces its own hormones in response to hypothalamic releasing hormones, e.g., adrenocorticotropic hormone ACTH, luteinizing hormone LH, follicle-stimulating hormone FSH, prolactin, growth hormone, thyroid-stimulating hormone TSH Thyroid Regulation of metabolism, development, and maturation... 

Opioid analgesics stimulate the release of ADH, prolactin, and somatotropin but inhibit the release of luteinizing hormone. These effects suggest that endogenous opioid peptides, through effects in the hypothalamus, regulate these systems (Table 31-1). 

Dafopoulos K, Mademtzis I, Vanakara P, et al. Evidence that termination of the estradiol-induced luteinizing hormone surge in women is regulated by ovarian factors. J Clin Endocrinol Metab. 2006 91 641-645. 

Fig. 6. Hormones of the hypothalamic-pituitary axis and the glands and target organs they regulate (ACTH = adrenocorticotropic hormone LH = luteinizing hormone FSH = follicle stimulating hormone TSH = thyroid stimulating hormone PRL = prolactin GH = growth hormone).

Smith, W., Hypothalamic regulation of pituitary secretion of luteinizing hormone. II. Feedback control of gonadotropin secretion, Bulletin of Mathematical Biology, Vol. 42, No. 1, 1980, pp. 57-78. 

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