Lutein supplements

Berendschot, T. T. J. M. et al. (2000). Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Investigative Ophthalmology and Visual Science 41 3322-3326. 

Bhosale P, Zhao DY, and Bernstein PS (2007), HPLC measurement of ocular carotenoid levels in human donor eyes in the lutein supplementation era, Invest. Ophthalmol. Visual Sci. 48 543-549. 

In summary, lutein supplementation has been shown to raise MPOD in the majority of subjects supplemented. In the few cases where no increases of MPOD could be observed, longer periods of supplementation (>6 months) and higher dosages (>20mg/day) may be necessary to cause significant... 

Aleman, T. S., J. L. Duncan et al. (2001). Macular pigment and lutein supplementation in retinitis pigmentosa and Usher syndrome. Invest. Ophthalmol. Vis. Sci. 42(8) 1873-1881. 

Johnson, E. J., K. A. McDonald et al. (2008b). Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women. Nutr. Neurosci. 11(2) 75-83. 

Thiirmann, P. A., W. Schalch et al. (2005). Plasma kinetics of lutein, zeaxanthin, and 3 -dehydro-lutein after multiple oral doses of a lutein supplement. Am. J. Clin. Nutr. 82(1) 88-97. 

Wenzel, A. J., J. P. Sheehan et al. (2007). Macular pigment optical density at four retinal loci during 120 days of lutein supplementation. Ophthal. Physiol. Opt. 27(4) 329-335. 

Bahrami, H, Melia, M, and Dagnelie, G, 2006. Lutein supplementation in retinitis pigmentosa PC-based vision assessment in a randomized double-masked placebo-controlled clinical trial [NCT00029289]. BMC Ophthalmol 6, 23. 

Koh, HH, Murray, IJ, Nolan, D, Carden, D, Feather, J, and Beatty, S, 2004. Plasma and macular responses to lutein supplement in subjects with and without age-related maculopathy A pilot study. Exp Eye Res 79, 21-27. 

Young, J.C. Abdel-Aal, E.S.M. Rabalski, I. Blackwell, B.A. 2007. Identification of synthetic regioisomeric lutein esters and their quantification in a commercial lutein supplement. J. Agric. Food Chem. 55 4965 972. 

Sasamoto Y, Gomi F, Sawa M, Tsujikawa M, Nishida K (2011) Effect of 1-year lutein supplementation on macular pigment optical density and visual function. Graefes Arch Clin Exp Ophthalmol 249 1847-1854. doi 10.1007/s00417-011-1780-z... 

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