Luteal phase deficiency

Ovulation with inadequate luteinization and reduced progesterone secretion during the luteal phase has been termed luteal phase deficiency. The contribution of luteal... 

Luteal phase deficiency is diagnosed when the time between ovulation and menses is 10 days or less. The most specific diagnostic information may be gained from an... 

Soules MR, McLachlan RI, Ek M, Dahl KD, Cohen NL, Bremner WJ. Luteal phase deficiency Characterization of reproductive hormones over the menstrual cycle. J Clin Endocrinol Metab 1989 69 804-12. 

Reproductive Effects. In samples from more than 200 men, no correlation between seminal fluid selenium and sperm count or mobility was detected. No significant increase in spontaneous abortions was reported among women chronically exposed to drinking water containing excessive amounts of selenium. Oral or injection treatment of rats with sodium selenate or selenite (at doses at least 8 times greater than those normally supplied by an adequate diet) has been shown to increase the number of abnormal sperm, produce testicular hypertrophy, or degeneration and atrophy in males, and to affect the estrous cycle in females. The animals in these studies were not mated, so it is not clear if fertility was affected. A small increase in the number of abnormal length estrous cycles was observed in mice exposed to selenium. Disturbances in the menstrual cycle (anovulation, short luteal and follicular phases) were also observed in monkeys treated orally with L-selenomethionine. Selenium deficiency has also been reported to cause decreased sperm production and motility in rats. The relevance of these reproductive effects of selenium in laboratory animals to potential reproductive effects in humans is not known. 

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