Lungs excretion from

Excretion is the process by which a substance leaves the body. The most common ways are via the kidneys and via the gut. Renal excretion is favored by water-soluble compounds that can be filtered (passively by the glomeruli) or secreted (actively by the tubuli) and that are collected into urine. Fecal excretion is followed by more lipid substances that are excreted from the liver into the bile, which is collected in the gut and passed out by the feces. Other routes of excretion are available through the skin and the lungs. 

Serum lipase is synthesized and stored in the granules of pancreatic acinar cells and is excreted from the apical poles of the acinar cells into the duct system of the gland. Lipases are produced not only in the pancreas but also at various sites in the human digestive tract [126][127]. Lipases are also found in leucocytes, adipose tissue, lung, and milk. 

Because a proportion of unmetabolized 1,2-dibromoethane is excreted from the lungs of guinea pigs (Plotnick and Conner 1976), measurement of the chemical in exhaled breath of humans is another potential method of monitoring human exposure. This has been done in a study using university student volunteers from a petrochemical plant area and a nonindustrial area. 1,2-Dibromoethane in exhaled breath was not found in either group of volunteers (Wallace et al. 1982). 

Gases and highly volatile chemicals can move out of the blood into the lungs, and be exhaled. Carbon dioxide, for example, is a metabolic product of many chemicals and also derives from the metabolism of essential molecules it is excreted from the body through the lungs. 

It is apparent from the schematic in Figure 3.2 that most of the losses of dmgs from the body are due to renal and fecal excretion. Some small fractions can also be lost through the lungs as a result of volatilization. Whatever is lost through renal and fecal excretion from humans is likely to end up in the sewer system, whereas most excretions from livestock end up in manure and farm runoff. Assuming that the concentration of the compound in the bloodstream is in equilibrium with that in the... 

Depending on the individual drug, elimination occurs primarily through excretion from the lungs, biotransformation in the liver, or a combination of these two methods.39 If the patient has any pulmonary or hepatic dysfunction, elimination of the anesthetic will be further delayed. 

Interestingly, it was shown that pentamidine slowly accumulates in and is slowly excreted from the major human organs detectable levels of pentamidine are present in some tissues as late as one year after the last dose. Tissue levels of pentamidine obtained in autopsy specimens from AIDS patients revealed that tissue accumulation was usually greater in liver, kidneys, adrenal glands, and spleen than in the lung. Nevertheless, there is no correlation between tissue levels and renal dysfunction, as measured by serum creatinine levels [149]. 

The final step involved in the action of a pollutant is excretion from the body. Excretion may take place through the kidneys, lungs, or intestinal tract. A pollutant may be excreted in its original form or as its metabolite(s), depending upon its chemical properties. Excretion is the most permanent means by which toxic substances are removed from the body. 

The fraction of the originally injected radioactivity excreted via the lungs decreased from 0.66% to 0.43 % from the 2nd to the 3rd hr. This was a... 

The fraction of the originally injected radioactivity excreted via the lungs decreased from 1.10% to 0.76% from the 2nd to the 3rd hr. There was a drop of 0.34/1.10 or 31 % in the concentration of radioactivity in the expired air. This corresponds to a drop of 35 % in the radioactivity in the expired air of HE, the normal subject. Obviously at this time radioactive carbon dioxide is being formed more rapidlj " in the addict than in the normal subject. 

Garlic is not suggested for nursing mothers, as it affects the taste of the milk and may interfere with nursing. It is excreted from the body through the lungs this may irritate loved ones and strangers alike. 

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