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Lung injury oxidant-related

Intratracheal instillation of crocidolite asbestos fibres resulted in an increased iNOS mRNA and protein expression in the lungs from wild-type mice (Dorger et al. 2002). In contrast, iNOS knockout mice displayed an attenuated oxidant-related tissue injury reflected in a decrease in protein leakage and lactate dehydrogenase release into the alveolar space as well as weaker nitrotyrosine staining of lung tissue compared to wild-type mice. [Pg.122]

Williams JP, Hernady E, Johnston CJ et al. (2004) Effect of administration of lovastatin on the development of late pulmonary effects after whole-lung irradiation in a murine model. Radiat Res 161 560-567 Yi ES, Williams ST, Lee H etal. (1996) Keratinocyte growth factor ameliorates radiation- and bleomycin-induced lung injury and mortality. Am J Pathol 149 1963 1970 Zhao W, Diz DI, Robbins ME (2007) Oxidative damage path-wiiys in relation to normal tissue injury. Br J Radiol 80 Spec No I S23-31... [Pg.241]

See other pages where Lung injury oxidant-related is mentioned: [Pg.222]    [Pg.222]    [Pg.600]    [Pg.412]    [Pg.584]    [Pg.435]    [Pg.78]    [Pg.78]    [Pg.247]    [Pg.265]    [Pg.867]    [Pg.867]    [Pg.701]    [Pg.247]    [Pg.2266]    [Pg.2269]    [Pg.377]    [Pg.751]    [Pg.4127]    [Pg.129]    [Pg.135]   


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