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Long-chain acyl-CoA hydrolase

Monoacylglycerol lipase Long-chain acyl-CoA hydrolase... [Pg.47]

Kawashima Y, Uy-Yu N, Kozuka H Sex-related difference in the inductions by perfluorooctanoic acid of peroxisomal fl-oxidation, microsomal 1-acylglycerophos-phocholine acyltransferase and cytosolic long-chain acyl-CoA hydrolase in rat liver. Biochem J 26 595-6Q0, 1989... [Pg.47]

Serine csterase.s AChE, butyrylcholinesterase, carboxylesterase, long-chain acyl-CoA hydrolase, fatty acid amide hydrolase Scr, His Jansz etai. (1959). Ktjrza and Ozols (1988), Kidd etal (2001), Quistad eta ., (2002b)... [Pg.706]

Beige, R.K., and Farstad, M. (1979) Eur. J. Biochem. 96, 393 1. Purification and characterization of long-chain acyl-CoA hydrolase from rat liver mitochondria. [Pg.154]

Miyazawa, S., Furuta, S. Hashimoto, T. (1981) r. J. Biochem. 117,425-430. Induction of a novel long-chain acyl-CoA hydrolase in rat liver by administration of peroxisome proliferators. [Pg.200]

Katoh, H., Kawashima, Y, Watanuki, H., Kozuka, H. Isono, H. (1991) BiocMm. Biophys. Acta. 920, 171-179. Effects of clofibric acid and tiadenol on cytosolic long-chain acyl-CoA hydrolase and peroxisomal P-oxidation in liver and extrahepatic tissues of rat. [Pg.200]

Yamada, 1, Furihata, T., lida, N., Watanabe, T., Hosokawa, M, Satoh, T., Someya, A., Nagaoka, I. Suga, T. (1997) Biochem Biophys. Res. Commun. 232, 198-203. Molecular cloning and expression of cDNAs encoding rat brain and liver cytosolic long-chain acyl-CoA hydrolases. [Pg.200]

Thiolester hydrolases (EC 3.1.2) play an important role in the biochemistry of lipids. They catalyze the hydrolysis of acyl-coenzyme A thiolesters of various chain lengths to free fatty acids and coenzyme A. The current list of over 20 specific enzymes includes acetyl-CoA hydrolase (EC 3.1.2.1), pal-mi toy 1-Co A hydrolase (EC 3.1.2.2), and an acyl-CoA hydrolase (EC 3.1.2.20) of broad specificity for medium- to long-chain acyl-CoA [128],... [Pg.55]

Release of the finished fatty acid occurs when the chain length reaches C]6 by action of thioester hydrolase, which is specific for long-chain acyl-CoA derivatives. A thioester hydrolase of mammary gland is specific for acyl residues of Cg, Cio, or C12. [Pg.379]

Table 1.- Specific activities of microsomal long chain acyl CoA synthetase and acyl CoA hydrolase from normal liver, host liver and... Table 1.- Specific activities of microsomal long chain acyl CoA synthetase and acyl CoA hydrolase from normal liver, host liver and...
Figure 3. Mitochondrial fatty acid oxidation. Long-chain fatty acids are converted to their CoA-esters as described in the text, and their fatty-acyl-groups transferred to CoA in the matrix by the concerted action of CPT 1, the acylcarnitine/carnitine exchange carrier and CPT (A) as described in the text. Medium-chain and short-chain fatty acids (Cg or less) diffuse directly into the matrix where they are converted to their acyl-CoA esters by a acyl-CoA synthase. The mechanism of p-oxidation is shown below (B). Each cycle of P-oxidation removes -CH2-CH2- as an acetyl unit until the fatty acids are completely converted to acetyl-CoA. The enzymes catalyzing each stage of P-oxidation have different but overlapping specificities. In muscle mitochondria, most acetyl-CoA is oxidized to CO2 and H2O by the citrate cycle (Figure 4) some is converted to acylcamitine by carnitine acetyltransferase (associated with the inner face of the inner membrane) and exported from the matrix. Some acetyl-CoA (if in excess) is hydrolyzed to acetate and CoASH by acetyl-CoA hydrolase in the matrix. Enzymes ... Figure 3. Mitochondrial fatty acid oxidation. Long-chain fatty acids are converted to their CoA-esters as described in the text, and their fatty-acyl-groups transferred to CoA in the matrix by the concerted action of CPT 1, the acylcarnitine/carnitine exchange carrier and CPT (A) as described in the text. Medium-chain and short-chain fatty acids (Cg or less) diffuse directly into the matrix where they are converted to their acyl-CoA esters by a acyl-CoA synthase. The mechanism of p-oxidation is shown below (B). Each cycle of P-oxidation removes -CH2-CH2- as an acetyl unit until the fatty acids are completely converted to acetyl-CoA. The enzymes catalyzing each stage of P-oxidation have different but overlapping specificities. In muscle mitochondria, most acetyl-CoA is oxidized to CO2 and H2O by the citrate cycle (Figure 4) some is converted to acylcamitine by carnitine acetyltransferase (associated with the inner face of the inner membrane) and exported from the matrix. Some acetyl-CoA (if in excess) is hydrolyzed to acetate and CoASH by acetyl-CoA hydrolase in the matrix. Enzymes ...
See other pages where Long-chain acyl-CoA hydrolase is mentioned: [Pg.150]    [Pg.150]    [Pg.150]    [Pg.150]    [Pg.50]    [Pg.221]    [Pg.373]    [Pg.181]    [Pg.138]    [Pg.373]    [Pg.561]    [Pg.595]   
See also in sourсe #XX -- [ Pg.29 ]



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1 -Acyl hydrolases

Acyl long-chain

Acyl-CoA

Acyl-CoA hydrolases

Long-chain acyl CoA

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